Synthetic Study of Glutamate Receptor Antagonistic Natural Product Based on C-H Amination Reaction
| Project/Area Number |
23790015
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Nagasaki University |
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Principal Investigator |
TAKAHASHI Keisuke 長崎大学, 大学院・医歯薬学総合研究科, 助教 (60380854)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 天然物 / 全合成 / カイトセファリン / C-Hアミノ化 / 複素環 / グルタミン酸受容体 / Overman転位 / 鈴木カップリング / ピロリジン / アミノ酸 |
|---|
| Research Abstract |
New methodology for synthesizing pyrroline derivatives was developed. The methodology was utilized for the total synthesis of kaitocephalin a natural glutamate receptor antagonist
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Report
(3 results)
Research Products
(62 results)
