Synthesis of electron withdrawing cyclopentadienides as new Lewis acid catalysts
| Project/Area Number |
23790027
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Meijo University |
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Principal Investigator |
TAKEO Sakai 名城大学, 薬学部, 助教 (90583873)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | テトラシアノシクロペンタジエニド / 酸 / 触媒 / スルホン / 有機化学 / 超強酸共役塩基 / ルイス酸 / 向山アルドール / 酸触媒 / 相間移動 / アニオン / 超強酸アニオン |
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| Research Abstract |
Superacid conjugate bases are widely used in reagents and catalysts. We established a general synthetic method for tetracyanocyclopentadienides, one of superacid conjugate bases, from sulfones and tetracyanothiophene. Various functionalization reactions on a cyclopentadienide ring were performed to give more substituent diversity.
The hydrolysis of O-TBS-menthol was accelerated by the addition of synthesized tetracyanocyclopentadienides in dichloromethane-1 M hydrochloric acid biphase system, in which the TBS group was usually rigid.
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Report
(4 results)
Research Products
(60 results)
