Development of Novel Chemoenzymatic Reaction System for OrganicSynthesis UtilizingIonic Polymers
| Project/Area Number |
23790031
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Meijo University (2012)
Kinki University (2011) |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 有機化学 / 触媒 / 高分子 / 酵素触媒反応 / リパーゼ / イオン液体 / 有機合成 / 光学分割 / 不斉合成 / イオン性ポリマー |
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| Research Abstract |
The use of a novel reaction medium provided by functionalized polymers could often bring a new strategy in the design of reagent or catalyst recycling systems. This work focused on the use of ionicacrylamide-based polymer for the design of novel chemoenzymaticreaction system. The lipase-catalyzed esterification reactions proceeded smoothly with high stereoselectivitiesin ionicacrylamide-based polymer solution or polymer gel. In addition, the enzymes can be easily recovered together with this ionic polymer and was reused without significant loss of catalytic activities.
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Report
(3 results)
Research Products
(53 results)
