Structure determination and elucidation of transport mechanism of mitochondrial inner membrane transporter
| Project/Area Number |
23790064
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Physical pharmacy
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
TAKEUCHI Koh 独立行政法人産業技術総合研究所, 創薬分子プロファイリング研究センター, 主任研究員 (20581284)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 構造生物学 / 核磁気共鳴 / 膜タンパク質 / タンパク質発現 / 立体構造解析 |
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| Research Abstract |
To contribute the understanding and cure of the human diseases associated with mitochondrial membrane transporters (MTPs), we developed prokaryotic expression systems for 13 types of MTPs for structure determination and elucidation of their transport mech
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Report
(3 results)
Research Products
(22 results)
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[Journal Article] A homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation2013
Author(s)
Davis MI, Sasaki AT, Shen M, Emerling BM, Thorne N, Michael S, Pragani R, Boxer M, Sumita K, Takeuchi K, Auld DS, Li Z, Cantley LC, Simenov A
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Journal Title
PLoS One.
Volume: 8
Issue: 1
Pages: e54127-e54127
DOI
Related Report
Peer Reviewed
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