Development of microsome electrode for efficient drugMetabolism assay
| Project/Area Number |
23790065
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Physical pharmacy
|
|---|
| Research Institution | National Institute of Advanced Industrial Science and Technology |
|---|
Principal Investigator |
MIE Yasuhiro 独立行政法人産業技術総合研究所, 生物プロセス研究部門, 主任研究員 (00415746)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 電気化学アッセイ / ミクロソームアッセイ / ミクロソーム / 薬物代謝 / ナノ構造界面電極 |
|---|
| Research Abstract |
Microsome containing human cytochrome P450s (CYPs) play the most crucial role in drug metabolism. Single nucleotide polymorphisms of CYPs are partially responsible for differences in drug effects among individuals. Also, drug metabolism via the microsome
|
Report
(3 results)
Research Products
(18 results)
