Development of helical nanotubes for recognizing bioactive oligopeptides
| Project/Area Number |
23790132
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Drug development chemistry
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| Research Institution | Kobe Gakuin University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | シクロデキストリン / 二量体 / らせん構造 / ホストゲスト化学 / シクロデキストリン二量体 / cyclodextrin |
|---|
| Research Abstract |
A synthetic method of 6A,6D-di-(aminoetylthio)-gamma-CD was established, so far. This AD-substituted gamma-CD can be available for comparison with AE-substituted one. The synthetic methods of the precursors of desirable 6A,6E-di-substituted-gammma- and 6A,6D-di-substituted-alpha-CDs were also established. It is now in progress that investigations of synthesis, structural characterizations and functionalities as host molecules of alpha- and gamma-CD dimers connected these precursors by several linkers.
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Report
(4 results)
Research Products
(23 results)
