Project/Area Number |
23790136
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Drug development chemistry
|
Research Institution | Osaka City University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 抗体 / ペプチド移植 / タンパク質工学 / 受容体 / 分子認識 / リガンド |
Research Abstract |
In this study, to develop a method for generating functional antibodies, we grafted the peptide fragment, which was derived from the proteinous ligand, onto the variable region of a human antibody. As the results, we succeeded in preparing the peptide-gra
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