Mechanisms underlying evolutionary architecture of primary sensory neurons in chordates
Project/Area Number |
23790234
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
General anatomy (including Histology/Embryology)
|
Research Institution | Jichi Medical University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 発生 / 進化 / 分化 / 一次感覚神経 / 脊髄神経節 / 神経堤細胞 / エンハンサー / Six遺伝子 |
Research Abstract |
We found 1) Six1 is a key regulator of transition from intramedullary primary sensory neurons to extramedullary sensory neurons during Xenopus development, 2) early expression of Six1 prevents the appearance of intramedullary sensory neurons in mouse spin
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Report
(3 results)
Research Products
(13 results)