Novel immunosuppressive protocol in whichdepleting donor dendritic-cells by anti-MHC-II antibodies.
Project/Area Number |
23790235
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
General anatomy (including Histology/Embryology)
|
Research Institution | Dokkyo Medical University |
Principal Investigator |
UETA Hisashi 獨協医科大学, 医学部, 准教授 (10364556)
|
Project Period (FY) |
2012 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 免疫組織学 / 樹状細胞 / cell trafficking / 移植免疫 / 免疫抑制 / 抗体 / MHC-II / ラット / MHC class II (MHC-II) / 肝臓 |
Research Abstract |
We identified 2 types of immunogeneic dendritic-cells in rat liver and developed a novel immunosuppressive protocol by depleting them using antibody against MHC-II.
|
Report
(3 results)
Research Products
(7 results)