| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
The variety of the cytoprotective effects of flavonoids is assumed to inhibit common molecular mechanisms. In this study, I investigated the functional and structural changes ofthe cell membrane by quercetin, one of the flavonoids, to elucidate the molecular mechanisms of inhibitory effect of flavonoids. I showed the possibilities that quercetin translocated PLD to plasma membrane and induced the expression of HO-1 which is the key molecule to exhibit cytoprotective effects.
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