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analysis of pathogeny of Herpes simplex virus 1 using original methods of recombination for virus genome

Research Project

Project/Area Number 23790511
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Virology
Research InstitutionNational Institute of Infectious Diseases

Principal Investigator

TANAKA Michiko  国立感染症研究所, その他部局等, 研究員 (10356248)

Project Period (FY) 2011-04-28 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords大腸菌 / HSV / 組換えHSV / 組換HSV / 組換えウイルス
Outline of Final Research Achievements

Recombination of HSV genome is complicate and is an obstacle for manufacture for gene therapy vector. In this study, we established new method for virus genome recombination and using this methods, analyze the HSV pathogenicity.

Report

(5 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (1 results)

All 2011

All Journal Article (1 results) (of which Peer Reviewed: 1 results)

  • [Journal Article] Herpes Simplex Virus 1 Protein Kinase Us3 and Major Tegument Protein UL47 Reciprocally Regulate Their Subcellular Localization in Infected Cells.2011

    • Author(s)
      Kato A., Liu Z., Minowa A., Imai T., Tanaka M., Sugimoto K., Nishiyama Y., Arii J., and Kawaguchi Y.
    • Journal Title

      Journal of Virology

      Volume: 85 Pages: 9599-9613

    • Related Report
      2011 Research-status Report
    • Peer Reviewed

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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