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The multiple epidemiological study on association between sleep-disordered breathing and depression in Japanese patients with type2 diabetes mellitus

Research Project

Project/Area Number 23790697
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Public health/Health science
Research InstitutionEhime University

Principal Investigator

FURUKAWA Shinya  愛媛大学, 大学院・医学系研究科, 准教授 (60444733)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords糖尿病 / うつ症状 / 睡眠呼吸障害 / 予後 / HbA1c / うつ病 / 疫学研究
Research Abstract

The prevalence of depression was 45.5% among Japanese subject with type2 diabetes mellitus. The prevalence of severe depression was 14.8% in our population. Severe depression group was higher HbA1c, higher BMI and younger than the group withoutdepression. The association between depression and sleep-disordered breathing was not significant. The association between depression and HbA1c was shown in our study. After adjusted several factor, HbA1c was independent associated factor for depression among Japanesepeople with type2 diabetes mellitus.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (26 results)

All 2013 2012 2011

All Journal Article (12 results) (of which Peer Reviewed: 10 results) Presentation (14 results)

  • [Journal Article] 糖尿病患者における抑うつ症状の頻度と教うつ症状(SDS)正常範囲SDS (40‐49)SDS 50以上Figure.1 糖尿病患者におけるうつ症状育入院による改善効果2013

    • Author(s)
      新谷哲司, 宮崎大輔, 庄島蘇音, 小川明子,河本絵里子, 西山麻里, 古川慎哉
    • Journal Title

      糖尿病

      Volume: 56巻 Pages: 1-7

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 糖尿病患者における抑うつ症状の頻度と教育入院による改善効果2013

    • Author(s)
      新谷哲司
    • Journal Title

      糖尿病

      Volume: 56 Pages: 1-7

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Suicide attempt by an overdose of sitagliptin, an oral hypoglycemic agent: a case report and a review of the literature2012

    • Author(s)
      Furukawa S, Kumagi T, Miyake T, Ueda T, Niiya T, Nishino K, Murakami S, Murakami M, Matsuura B, Onji M
    • Journal Title

      Endocrine J

      Volume: 59 Pages: 329-33

    • NAID

      10030749488

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ダウン症候群を合併した C 型慢性肝炎にインターフェロン治療でウイルス学的著効が得られた 1 例2012

    • Author(s)
      松田 隼弥, 古川 慎哉, 横本 祐希, 阿部 陽介, 高木 康平, 垣生 恭佑, 木阪 吉保, 徳本 良雄, 眞柴 寿枝, 廣岡 昌史, 阿部 雅則, 日浅 陽一, 恩地 森一
    • Journal Title

      肝臓

      Volume: 53巻 Pages: 201-5

    • NAID

      10030625348

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 糖尿病および糖尿病関連疾患と ED との関連性2012

    • Author(s)
      古川慎哉
    • Journal Title

      kyo

      Volume: 172巻 Pages: 10-15

    • Related Report
      2012 Final Research Report
  • [Journal Article] 糖尿病および糖尿病関連疾患とEDとの関連性2012

    • Author(s)
      古川慎哉
    • Journal Title

      Kyo

      Volume: 172 Pages: 10-15

    • Related Report
      2012 Annual Research Report
  • [Journal Article] ソラフェニブにより消化管出血を発症した進行肝細胞癌の2例2011

    • Author(s)
      渡辺崇夫, 日浅陽一, 廣岡昌史, 木阪吉保, 古川慎哉, 阿部雅則, 村上英広, 池田宜央, 松浦文三, 恩地森一
    • Journal Title

      Gastroenterological Endoscopy

      Volume: 53 Pages: 1626-33

    • NAID

      10029092728

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Ulcerative colitis complicated with primary biliary cirrhosis.2011

    • Author(s)
      Tada F, Abe M, Nunoi H, Azemoto N, Mashiba T, Furukawa S, Kumagi T, Murakami H, Ikeda Y, Matsuura B, Hiasa Y, Onji M
    • Journal Title

      Intern Med

      Volume: 50 Pages: 2323-7

    • NAID

      130001087740

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Aerobic exercise improves insulin resistance and decreases body fat and serum levels of leptin in patients with hepatitis C virus.2011

    • Author(s)
      Konishi I, Hiasa Y, Tokumoto Y, Abe M, Furukawa S, Toshimitsu K, Matsuura B, Onji M.
    • Journal Title

      Hepatol Res.

      Volume: 41 Pages: 928-35

    • NAID

      10031144167

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] B cell-activating factor controls the production of adipokines and induces insulin resistance.2011

    • Author(s)
      Hamada M, Abe M, Miyake T, Kawasaki K, Tada F, Furukawa S, Matsuura B, Hiasa Y, Onji M.
    • Journal Title

      Obesity

      Volume: 19 Pages: 1915-22

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Mutational analysis of predicted extracellular domains of human growth hormone secretagogue receptor 1a2011

    • Author(s)
      Ueda T, Matsuura B, Miyake T, Furukawa S, Abe M, Hiasa Y, Onji M.
    • Journal Title

      Regul Pept

      Volume: 17 Pages: 28-35

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Safety and immunogenicity of hepatitis B surface antigen-pulsed dendritic cells in patients with chronic hepatitis B2011

    • Author(s)
      Akbar SM, Furukawa S, Horiike N, Abe M, Hiasa Y, Onji M.
    • Journal Title

      J Viral Hepat

      Volume: 18 Pages: 408-14

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Clinical characteristics of diabetic patients beyond age of 85 in Japanese populations.2013

    • Author(s)
      Toshiya Matsuda, Shinya Furukawa,Teruki Miyake, Teruhisa Ueda, Tetsuji Niiya, Teru Kumagi, Takenori Sakai, Hisaka Minami, Hiroaki Miyaoka, Bunzo Matsuura, Takeshi Tanigawa, Morikazu Onji
    • Organizer
      4th Asian Association for the Study of Diabetes
    • Place of Presentation
      京都
    • Year and Date
      2013-10-26
    • Related Report
      2012 Final Research Report
  • [Presentation] 糖尿病における睡眠呼吸障害(sleep-disorder breathing; SDB)と細小血管障害に関する多施設共同横断調査(道後STUDY)2013

    • Author(s)
      古川 慎哉, 山本 晋, 三宅 映己, 上田 晃久, 新谷 哲司, 南 尚佳, 宮内 省蔵, 酒井 武則, 宮岡 弘明, 谷口 嘉康, 松浦 文三 恩地森一 2.4thAsian Association for the Study of Diabetes 京都 2013 年 10 月 26 日 Clinical characteristics of diabetic patients beyond age of 85 in Japanese populations. Toshiya Matsuda, Shinya Furukawa,Teruki Miyake, Teruhisa Ueda, Tetsuji Niiya, Teru Kumagi, Takenori Sakai, Hisaka Minami, Hiroaki Miyaoka, Bunzo Matsuura, Takeshi Tanigawa, Morikazu Onji 3.American Diabetes Association 72th 2013 Philadelphia 2013 年 6 月 21 日から 25 日 Sleep-Disordered breathing as a modifiable Risk Factor for Microvascular Complications in Japanese Type 2 Diabetes Mellitus Shinya Furukawa, Isao Saito, Teruki Miyake, Teruhisa Ueda, Tetsuji Niiya, Teru Kumagi, Takenori Sakai, Hisaka Minami, Hiroaki Miyaoka, Bunzo Matsuura, Takeshi Tanigawa, Morikazu Onji 4.第55回 日本糖尿病学会年次学術集会 横浜 2013 年 5 月 17 日から 19 日 パシフィコ横浜 糖尿病における睡眠呼吸障害に関する多施設共同疫学調査(道後 STUDY) 古川 慎哉, 山本 晋, 三宅 映己, 上田 晃久, 新谷 哲司, 南 尚佳, 宮内 省蔵, 酒井 武則, 宮岡 弘明, 谷口 嘉康, 松浦 文三 恩地森一,谷川武 6.研究組織 (1)研究代表者 古川 慎哉(Furukawa Shinya)
    • Organizer
      第50回 日本糖尿病学会中国四国地方会総会
    • Place of Presentation
      くにびき メッセ 島根
    • Related Report
      2012 Final Research Report
  • [Presentation] Sleep-Disordered breathing as a modifiable Risk Factor for Microvascular Complications in Japanese Type 2 Diabetes Mellitus2013

    • Author(s)
      Shinya Furukawa, Isao Saito, Teruki Miyake, Teruhisa Ueda, Tetsuji Niiya, Teru Kumagi, Takenori Sakai, Hisaka Minami, Hiroaki Miyaoka, Bunzo Matsuura, Takeshi Tanigawa, Morikazu Onji
    • Organizer
      American Diabetes Association 72th 2013
    • Place of Presentation
      Philadelphia
    • Related Report
      2012 Final Research Report
  • [Presentation] 糖尿病における睡眠呼吸障害に関する多施設共同疫学調査(道後 STUDY)2013

    • Author(s)
      古川 慎哉, 山本 晋, 三宅 映己, 上田 晃久, 新谷 哲司, 南 尚佳, 宮内 省蔵, 酒井 武則, 宮岡 弘明, 谷口 嘉康, 松浦 文三 恩地森一,谷川武
    • Organizer
      第55回 日本糖尿病学会年次学術集会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] 糖尿病における睡眠呼吸障害による細小血管障害との関連性についての多施設共同疫学調査(道後STUDY)2013

    • Author(s)
      古川慎哉
    • Organizer
      第56回 日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Related Report
      2012 Annual Research Report
  • [Presentation] 糖尿病における睡眠呼吸障害に関する多施設共同疫学調査(道後STUDY)2012

    • Author(s)
      古川慎哉
    • Organizer
      第55回 日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] Sleep-Disordered breathing as a modifiable Risk Factor for Microvascular Complications in Japanese Type 2 Diabetes Mellitus2012

    • Author(s)
      Furukawa S
    • Organizer
      American Diabetes Association 72th 2013
    • Place of Presentation
      USA, Philadelphia
    • Related Report
      2012 Annual Research Report
  • [Presentation] 糖尿病における睡眠呼吸障害(sleep-disorder breathing; SDB)と細小血管障害に関する多施設共同横断調査(道後STUDY)2012

    • Author(s)
      古川慎哉
    • Organizer
      日本糖尿病学会中国四国地方会第50回総会
    • Place of Presentation
      島根
    • Related Report
      2012 Annual Research Report
  • [Presentation] Clinical characteristics of diabetic patients beyond age of 85 in Japanese populations.2012

    • Author(s)
      Matsuda T
    • Organizer
      4th Asian Association for the Study of Diabetes
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] 糖尿病とED2012

    • Author(s)
      古川慎哉
    • Organizer
      日本性機能学会総会(招待講演)
    • Place of Presentation
      鹿児島
    • Related Report
      2011 Research-status Report
  • [Presentation] 糖尿病患者における牛乳・乳製品摂取習慣とBMIに関する多施設共同疫学調査2011

    • Author(s)
      古川慎哉, 三宅映己, 上田晃久, 永井祥子, 利光久美子, 松浦文三, 恩地森一
    • Organizer
      日本肥満治療学会
    • Place of Presentation
      京都
    • Related Report
      2011 Research-status Report
  • [Presentation] 糖尿病におけるIIEF(International Index of Erectile Function)5に関する多施設共同疫学調査2011

    • Author(s)
      池田健太郎, 宮岡弘明, 新谷哲司, 酒井武則, 宮内省蔵, 南尚佳, 鳥巣真幹, 三宅映己, 古川慎哉
    • Organizer
      日本性機能学会
    • Place of Presentation
      岡山
    • Related Report
      2011 Research-status Report
  • [Presentation] 糖尿病とED UPTADE2011

    • Author(s)
      古川慎哉
    • Organizer
      日本性機能学会西武総会(招待講演)
    • Place of Presentation
      岡山
    • Related Report
      2011 Research-status Report
  • [Presentation] 糖尿病患者における潜在性甲状腺機能低下症に関する多施設共同疫学調査2011

    • Author(s)
      古川慎哉, 三宅映己, 上田晃久, 新谷哲司, 宮内省蔵, 酒井武則, 南尚佳, 宮岡弘明, 谷口嘉康, 松浦文三, 恩地森一
    • Organizer
      日本甲状腺学会総会
    • Place of Presentation
      大阪
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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