Project/Area Number |
23790714
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Public health/Health science
|
Research Institution | Kurume University |
Principal Investigator |
YOKOI Kanako 久留米大学, 医学部, 助教 (80569385)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 疫学 / エンドセリン / 死亡率 / 追跡理 / エンドセリン-1 / 前向き研究 / 社会医学 |
Research Abstract |
Plasma ET-1 level is a predictor of mortality in patients with several types of cancers. However, all previous mortality data have been derived from patients with existing pathological cardiovascular disease and malignancies. Accordingly, we examined whether the plasma ET-1 level would predict 10-year cardiovascular, cancer and all-cause deaths in a general population. This is the first report demonstrating that the plasma ET-1 level is a predictor of 10-year mortality in subjects without apparent cardiovascular disease or malignancies in the general population.
|