Role of oxytocin and oxytocin receptor in stress responses in the brain
| Project/Area Number |
23790735
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | Kochi University |
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Principal Investigator |
YAMAGUCHI Naoko 高知大学, 教育研究部医療学系, 助教 (50380324)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | ストレス / オキシトシン / エストロゲン |
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| Research Abstract |
Oxytocin is one of the important factors to regulate stress responses in the brain. In this study, I examined the role of brain oxytocin system after restraint stress exposure using oxytocin receptor knockout female mice. The present results suggest that oxytocin receptor mediate acute restraint stress-induced expression of stress-related factors including corticotropin-releasing factor in the brain.
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Report
(3 results)
Research Products
(13 results)
