| Project/Area Number |
23790753
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
General internal medicine (including Psychosomatic medicine)
|
|---|
| Research Institution | Teikyo University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2012: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Keywords | 東洋医学 / 非アルコール性脂肪性肝炎 / 漢方薬 |
|---|
| Research Abstract |
In the present study, we examined the effects of Japanese herbal medicines on two kinds of model mice of NASH (methionine- and choline-deficient (MCD) diet-fed db/db mice and high-fat (HF) diet-fed db/db mice). As a result, sho-saiko-to (TJ-9) and juzen-taiho-to (TJ-48) significantly inhibited NASH in the MCD diet model, and inchin-ko-to (TJ-135) in addition to TJ-9 and TJ-48 significantly inhibited NASH in the HF diet model.
|
