Non-invasive therapeutic angiogenesis for critical limb ischemia
| Project/Area Number |
23790884
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Circulatory organs internal medicine
|
|---|
| Research Institution | Nippon Medical School |
|---|
Principal Investigator |
TARA Shuhei 日本医科大学, 医学部, 助教 (80465319)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Keywords | 重症虚血肢 / 血管新生 / 体外衝撃波 / 末梢動脈疾患 / 非侵襲治療 / 血管新生治療 / 微小循環血流 / 非侵襲的治療 |
|---|
| Research Abstract |
We investigated the safety and efficacy of a low-energy shock waves therapy in order to develop a non-invasive method for intractable peripheral arterial disease. To assess microcirculation blood flow, transcutaneous oxygen tension (TcPO2), skin perfusion pressure (SPP) and 99mtechnetium-tetrofosmin (99mTc-TF) scintigraphy were performed before and after therapy. The value of TcPO2 and perfusion index using 99mTc-TF increased significantly. SPP tended to increase after therapy, but there was no significant difference. There was no adverse event such as bleeding and pain, despite all the patientsin this study were taking one or more antiplatelet agents.
|
Report
(3 results)
Research Products
(3 results)
