| Project/Area Number |
23790908
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | 独立行政法人国立がん研究センター (2012)
Tottori University (2011) |
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Principal Investigator |
MATSUMOTO Shingo 独立行政法人国立がん研究センター, 臨床開発センター, 医師 (10392341)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 肺癌 / 末梢血癌細胞 / ゲノム異常 / 遺伝子変異 / バイオマーカー / 肺がん / 微量DNA / 遺伝子異常 / シークエンス / 末梢循環血液 / 腫瘍細胞 / ゲノム異常細胞 / 抗がん剤感受性 |
|---|
| Research Abstract |
Personalized medicine based on appropriate molecular biomarkers is hoped to improve prognoses of lung cancer patients. Biomarker analyses with circulating tumor cells or cell-free DNA (i.e., liquid biopsy) are quick, simple and non-invasive for advanced lung cancer patients. I established a rapidly and simultaneously detecting system of multiple genetic alterations from limited amounts of samples for efficiently selecting therapeutic populations.
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