| Project/Area Number |
23790940
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Kidney internal medicine
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2011: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
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| Keywords | IgA 腎症 / 腎細動脈硝子化 / IgA腎症 / 腎病理学的予後予測因子 / Oxford分類 / 腎予後 / コホート内症例対照研究 / 腎予後予測因子 / 病理組織学的所見 |
|---|
| Research Abstract |
In patients with IgA nephropathy, one of the major causes of end-stage kidney disease in Japan, little information is available about the factors which affect the histopathological vascular lesion except for hypertension. The present study identified age (especially >=25 years), hypertension (especially mean arterial pressure >=92mmHg) and hyperuricemia. These results strongly suggest that hyperuricemia may induce hypertensive vascular lesions, partially leading to progression of IgA nephropathy
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