| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
The Aim of this study is to investigate the induction of anti-inflammatory macrophages in experimental nephritis and to verify its potential use in nephritis therapy. We research for molecular biological characteristics of inducted anti-inflammatory macrophages in vitro, and then verify that adoptive transfer of these macrophages might have effectiveness in experimental nephritis. In human glomerulonephritis, we assess that macrophage phenotype might have relevance to disease activity and confirm that the importance of to evaluate the macrophage phenotype when making histological decisions about renal biopsy histology.
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