Identification and functional analysis of novel MR co-regulator
| Project/Area Number |
23791051
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Endocrinology
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| Research Institution | Keio University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | アルドステロン / 転写 / 高血圧 / MR / エピゲノム |
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| Research Abstract |
We identified p150 as a novel MR co-regulator. P150 interacts with MR in a ligand dependent manner and acts as a co-repressor. It is possible that p150 plays an important role in the pathophysiology of essential hypertension.
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Report
(3 results)
Research Products
(9 results)
