| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Research Abstract |
Hematopoietic stem cells (HSC) are a subset of cells that are capable of self-renewal and differentiation into all mature blood cell lineages. In this study, we identified the common precursors of primitive erythrocytes and multipotent hematopoietic cells in early mouse development before the emergence of HSC. We compared the gene expression profiles between pre-HSC stage hematopoietic cells and HSC. Though the analysis, we identified genes distinctly expressed between these early progenitors and stem cells, suggesting the involvement of these genes into the stemness of blood cell system.
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