| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
Atmospheric plasma has been used as clinical treatment equipment originally for thermal burn, and recently this equipment is applied for diabetic skin ulcer. These previous studies showed that plasma have an effect on cell proliferation through cell growth factor. In this study, we examined the effect of inhalation of atmospheric plasma on hypoxic encephalopathy with rat model. Neonatal hypoxic encephalopathy is very difficult condition and there is no effective treatment for damaged brain at present. This study showed that inhalation of plasma could introduce angiogenesis and neurogenesis. The result also showed that inhalation of plasma effect on hemodynamics such as reducing blood pressure and gaining the heart rate. These effects are suspected to relate to nitric oxide produced by vascular endothelial cell.
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