| Project/Area Number |
23791252
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dermatology
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| Research Institution | Yamagata University |
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Principal Investigator |
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| Research Collaborator |
HOZUMI Yutaka 山形大学, 医学部, 技術専門員
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 色素細胞 / 遺伝子変異 / ウイルス感染 / RNA 編集 / 色素異常症 / RNA編集 / メラノサイト / 遺伝性対側性色素異常症 / 遺伝子診断 / 安定ノックダウン / 悪性黒色腫細胞 |
|---|
| Research Abstract |
I have investigated pathomechanisms of dyschromatosis symmetricahereditaria (DSH). I have collected 43 samples of patients with DSH including a Turkishpatient and genetically diagnosed them. The results have been reported. And Iestablished the ADAR1-knockdown melanoma cells, which are model cells for DSH. Then,using the knockdown cells I found some interesting data showing association betweenvirus infection and DSH.
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