Analysis of ma1,candidate responsible gene for atopic dermatitis, andelucidation of molecular mechanism for the dermatitis caused by ma1 deficiency

Research Project

Project/Area Number	23791290
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Dermatology
Research Institution	Keio University
Principal Investigator	SHIOHAMA Aiko 慶應義塾大学, 医学部, 特任助教 (40383731)
Project Period (FY)	2011 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords	アトピー性皮膚炎 / モデルマウス / ゲノムシーケンシング / フィラグリン / SG1 / 表皮
Research Abstract	We established matted mice （ma^-）strain previously, which develop spontaneousdermatitis in specific-pathogen-free conditions. And we examined Matted wasresponsible for the dermatitis phenotype and corresponds to a nonsense mutation inthe ma1 gene. The aim

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(3 results)