The role of Histatin-1 ectopically expressed in human melanoma cells
| Project/Area Number |
23791293
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|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dermatology
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|---|
| Research Institution | Keio University |
|---|
Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 悪性黒色腫 |
|---|
| Research Abstract |
HTN-1, a saliva-specific antimicrobial secretory peptide, was ectopically expressed inhuman MM and contributed to its metastatic capacity and immunosuppressive activity,suggesting that HTN-1 was an attractive diagnostic marker and a therapeutic target for
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Report
(3 results)
Research Products
(38 results)
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[Journal Article] Autocrine and paracrine loops between cancer cells and macrophages promote lymph node metastasis via CCR4/CCL22 in head and neck squamous cell carcinoma2013
Author(s)
Tsujikawa T, Yaguchi T, Ohmura G, Ohta S, Kobayashi A, Kawamura N, Fujita T, Nakano H, Shimada T, Takahashi T, Nakao R, Yanagisawa A, Hisa Y, Kawakami Y
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Journal Title
Int J Cancer
Volume: 132(12)
Issue: 12
Pages: 2755-2766
DOI
Related Report
Peer Reviewed
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[Presentation] Role of IL6/IL8-NF-KB AXIS in the Immunosuppression and resistance to immunotherapy2011
Author(s)
Yutaka Kawakami, Hiroshi Nishio, Tomonori Yaguchi, Yoshie Kawase, Azusa Ohizumi, Shinobu Noji, Toshiharu Sakurai, Kazuo Umezawa, Tomonobu Fujita
Organizer
26th Annual Meeting Society for Immunotherapy of Cancer
Place of Presentation
North Bethesda, MD, USA
Related Report
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