Clinical study of novel treatment for drug-inducedhyperprolactinemia
Project/Area Number |
23791318
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Psychiatric science
|
Research Institution | University of Fukui |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 統合失調症 / 薬剤性高プロラクチン血症 / pramipexole / 高プロラクチン血症 / 臨床精神薬理 |
Research Abstract |
This pilot study aimed to evaluate the efficacy and tolerability of a low dose of pramipexole, a preferential dopamine D3 receptor agonist, in the treatment of antipsychotics -induced hyperprolactinemia. Forty male patients with schizophrenia who were showing hyperprolactinemia were selected. A few subjects are under treatment withadjunctive low-dosage pramipexole. We reported one of the cases who showed risperidone-induced hyperprolactinemia and ED, each of which was improved successfully without any adverse effect such as worsening psychosis.
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Report
(3 results)
Research Products
(5 results)