Research Project
Grant-in-Aid for Young Scientists (B)
We recently reported a significant association between schizophrenia and SNP rs4950928, which is located in the promoter region of the CHI3L1 gene, in a Japanese population. The aim of this study is to see the effect of CHI3L1 gene on various phenotypes of brain, like neurocognition, neuroimaging, neurophysiology, personality trait and gene expressions. We also investigated the differential expression of this gene in schizophrenia. We found the differential expression of CHI3L1 gene in schizophrenia. We also found the association between the risk SNP and the personality trait; Self-Transcendence or the expression of this gene and protein.
All 2013 2012 2011
All Journal Article (12 results) (of which Peer Reviewed: 10 results) Presentation (8 results) Book (2 results)
Schizophr Res
Volume: e-pub
Schizophrenia Bulletin.
Schizophrenia Bulletin
Schizophr Res,
Volume: 141(2-3): Issue: 2-3 Pages: 277-278
10.1016/j.schres.2012.08.015
Psychiatry Res
Volume: (Epub ahead of print) Issue: 1 Pages: 7-11
10.1016/j.psychres.2011.12.018
Am J Med Genet B Neuropsychiatr Genet
Volume: 159B(4) Issue: 4 Pages: 405-413
10.1002/ajmg.b.32043
PLoS ONE
Volume: 7 Issue: 4 Pages: e35696-e35696
10.1371/journal.pone.0035696
Neurosci Lett
Volume: 513(3) Pages: 204-208
Volume: (Epub ahead of print) Issue: 2 Pages: 204-208
10.1016/j.neulet.2012.02.039
World J Biol Psychiatry
Volume: e-pub Issue: 2 Pages: 100-13
10.3109/15622975.2011.591826
World J Biol Psychiatry.
Volume: e-pub Issue: 2 Pages: 114-20
10.3109/15622975.2011.604350