Prediction of Targeted Therapy Outcome for Fatty Acid Synthase by Acetate PET
Project/Area Number |
23791403
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Radiation science
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Research Institution | National Institute of Radiological Sciences |
Principal Investigator |
YOSHII Yukie 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 研究員 (10397242)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 核医学(PETを含む) / 治療効果予測 / PET / 分子標的治療 / 事前治療効果予測 / 酢酸PET |
Research Abstract |
Here, we showed the method to predict FASN-targeted therapy outcome using acetate PET and presented mechanisms of FASN-targeted therapy to provide the treatment strategy of FASN-targeted therapy.
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Report
(3 results)
Research Products
(9 results)
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[Journal Article] Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy outcome.2013
Author(s)
Yoshii Y, Furukawa T, Oyama N, Hasegawa Y, Kiyono Y, Nishii R, Waki A, Tsuji AB, Sogawa C, Wakizaka H, Fukumura T, Yoshii H, Fujibayashi Y, Lewis JS, Saga T.
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Journal Title
PLOS ONE
Volume: 8
Issue: 5
Pages: e64570-e64570
DOI
Related Report
Peer Reviewed
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[Journal Article] Fatty Acid Synthase Is a Key Target in Multiple Essential Tumor Functions of Prostate Cancer: Uptake of Radiolabeled Acetate as a Predictor of the Targeted Therapy Outcome2013
Author(s)
Yoshii Y, Furukawa T, Oyama N, Hasegawa Y, Kiyono Y, Nishii R, Waki A, Tsuji AB, Sogawa C, Wakizaka H, Fukumura T, Yoshii H, Fujibayashi Y, Lewis JS, and Saga T
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Journal Title
PLOS ONE
Volume: in press
Related Report
Peer Reviewed
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[Presentation] Fatty acid synthase is a key target to suppress tumor multiple functions: [1-11C]acetate PET as a predictor of the targeted therapy outcome2012
Author(s)
Yukie Yoshii, Takako Furukawa, Nobuyuki Oyama, Yoko Hasegawa, Yasushi Kiyono, Ryuichi Nishii, Atsushi Tsuji, Chizuru Sogawa, Hidekatsu Wakizaka, Hiroshi Yoshii, Yasuhisa Fujibayashi, Tsuneo Saga
Organizer
2012 World Molecular Imaging Congress
Place of Presentation
Dublin, Ireland
Related Report
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[Presentation] Fatty acid synthase is a key target to suppress tumor multiple functions: [1-11C]acetate PET as a predictor of the targeted therapy outcome2012
Author(s)
Yoshii Y, Furukawa T, Oyama N, YHasegawa Y, Kiyono Y, Nishii R, Tsuji AB, Sogawa C, Wakizaka H, Yoshii H, Fujibayashi Y, Saga T
Organizer
2012 World Molecular Imaging Congress
Place of Presentation
Dublin, Ireland
Related Report
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