| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
We performed comparative study of mannan-coated ultrasmall superparamagnetic iron oxide(mannan-coated USPIO), mannandextran-coated USPIO, and dextran-coated USPIO in the uptake bythe atherosclerotic wall using MRI and histology. Our histological and imaging analyses showed that mannan-coated USPIO and mannandextran-coated USPIO were taken up to a greater degree than dextran-coated USPIO. We suggest that mannan-coated particles are useful for the atherosclerotic imaging.
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