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Software development and three-dimensional quantitative analysis to establish multidisciplinary diagnosis for pulmonary adenocarcinoma

Research Project

Project/Area Number 23791417
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionOsaka University

Principal Investigator

YANAGAWA Masahiro  大阪大学, 医学系研究科, 助教 (00546872)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords肺腺癌 / 病理学的国際分類 / 病理学的浸潤部 / 病理学的非浸潤部 / すりガラス成分 / 3 次元画像解析 / 病理学的国際新分類 / 3次元画像解析 / 日本
Research Abstract

A custom-developed software can segment solid portion and ground-glass opacity (GGO) using the previously-reported threshold selection method for segmenting gray-level images, and can eliminate vessels on CT using 3-dimensionalmulti-scale line filter for segmentation and visualization of curvilinear structures such as vessels, resulting in calculating a rate of pure solid portion volume to whole tumor volume (%Solid) regardless of distribution of solid portions in nodule. Three-dimensional %Solid of adenocarcinomas is feasible for estimating prognosis. Nodule with %Solid>=63% significantly contributed to short overall and disease-free survival.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (8 results)

All 2012 2011

All Presentation (8 results)

  • [Presentation] Three-dimensional (3-D) quantitative analysis of preoperative CT images in pathological stage I pulmonary adenocarcinomas: Correlation with prognostic factors2012

    • Organizer
      Radiological Society of North America 97th Scientific Assembly and Annual Meeting (RSNA 2011)
    • Place of Presentation
      マコーミックプレイス・コンベンションセンター(USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] 3次元定量的CT画像解析による予後予測:肺腺癌(病理学的病期分類I期)での検討2012

    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Related Report
      2012 Final Research Report
  • [Presentation] Management and Diagnostic Imaging for Minute Pulmonary Nodules with or without Ground-Glass Opacity Radiological Society of North America2012

    • Organizer
      98th Scientific Assembly and Annual Meeting (RSNA 2012)
    • Place of Presentation
      マコーミックプレイス・コンベンションセンター(USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] 3次元定量的CT画像解析による予後予測:肺腺癌(病理学的病期分類I期)での検討2012

    • Author(s)
      梁川 雅弘
    • Organizer
      第71回日本医学放射線学会総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Management and Diagnostic Imaging for Minute Pulmonary Nodules with or without Ground-Glass Opacity2012

    • Author(s)
      梁川 雅弘
    • Organizer
      Radiological Society of North America 98th Scientific Assembly and Annual Meeting (RSNA 2012)
    • Place of Presentation
      マコーミックプレイス・コンベンションセンター(USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 3 次元定量的 CT 画像解析による予後予測:肺腺癌(病理学的病期分類I期)での検討2011

    • Organizer
      第52回日本肺癌学会総会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 3次元定量的CT画像解析による予後予測:肺腺癌(病理学的病期分類I期)での検討2011

    • Author(s)
      梁川雅弘、井上匡美、澄川裕充、本多修、小山光博、奥村明之進、富山憲幸
    • Organizer
      第52 回日本肺癌学会総会
    • Place of Presentation
      大阪
    • Related Report
      2011 Research-status Report
  • [Presentation] Three-dimensional (3-D) quantitative analysis of preoperative CT images in pathological stage I pulmonary adenocarcinomas: Correlation with prognostic factors.2011

    • Author(s)
      Yanagawa M, Tanaka Y, Morii E, Inoue M, Gyobu T, Kawata Y, Kawai M, Sumikawa H, Koyama M, Honda O, Johkoh T, Okumura M, Tomiyama N
    • Organizer
      Radiological Society of North America 97th Scientific Assembly and Annual Meeting (RSNA 2011)
    • Place of Presentation
      Chicago, U.S.A.
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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