Project/Area Number |
23791417
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Radiation science
|
Research Institution | Osaka University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 肺腺癌 / 病理学的国際分類 / 病理学的浸潤部 / 病理学的非浸潤部 / すりガラス成分 / 3 次元画像解析 / 病理学的国際新分類 / 3次元画像解析 / 日本 |
Research Abstract |
A custom-developed software can segment solid portion and ground-glass opacity (GGO) using the previously-reported threshold selection method for segmenting gray-level images, and can eliminate vessels on CT using 3-dimensionalmulti-scale line filter for segmentation and visualization of curvilinear structures such as vessels, resulting in calculating a rate of pure solid portion volume to whole tumor volume (%Solid) regardless of distribution of solid portions in nodule. Three-dimensional %Solid of adenocarcinomas is feasible for estimating prognosis. Nodule with %Solid>=63% significantly contributed to short overall and disease-free survival.
|