| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Research Abstract |
Synchrotron microbeam radiation therapy（SMRT) permits the delivery of very high radiation doses to the tumors in a single fraction. In this study, we have challenged to evaluate normal tissue tolerance and mortality by SMRT to the brain of the mice with comparing to broad beam irradiation. Our results including histopathological findings, immunohistologic analysis and functional analysis indicated that the SMRT enables to deliver extremely high doses without loss of normal tissue function.
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