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Radiofrequency ablation of rabbit VX2 liver tumors model in combination with immunostimulant agent

Research Project

Project/Area Number 23791437
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionOsaka City University

Principal Investigator

OKUMA Tomohisa  大阪市立大学, 大学院・医学研究科, 講師 (50445029)

Research Collaborator KAGEYAMA Ken  大阪市立大学, 大学院・医学研究科, 大学院生
HAMAMOTO Shinichi  大阪市立大学, 大学院・医学研究科, 病院講師 (80711788)
YAMAMOTO Akira  大阪市立大学, 大学院・医学研究科, 講師 (60419695)
MATSUOKA Toshiyuki  大阪市立大学, 大学院・医学研究科, 准教授 (40295697)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywordsラジオ波凝固療法 / 実験腫瘍 / 免疫賦活 / ラジオ波凝固
Research Abstract

To evaluate anti-tumor immunity activated by radiofrequency ablation combination with immno-stimulant agent, we examined end-point survival and local, distant tumor for combination therapy of rabbit VX2 liver model. Untreated control group, radiofrequency

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (7 results)

All 2013 2012 2011 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (3 results)

  • [Journal Article] Radiofrequency ablation and immunostimulant OK-432:combination therapy enhances systemic antitumor immunity for treatment of VX2 lung tumor model2013

    • Author(s)
      Hamamoto S, Okuma T,Yamamoto A, et al.
    • Journal Title

      Radiology

      Volume: 267 Pages: 405-413

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Radiofrequency Ablation and Immunostimulant OK-432: Combination Therapy Enhances Systemic Antitumor Immunity2013

    • Author(s)
      Shinichi Hamamoto, Tomohisa Okuma et al
    • Journal Title

      Radiology 120249; Published online February 25, 2013

      Volume: in press Issue: 2 Pages: 405-413

    • DOI

      10.1148/radiol.13120249

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of postoperative pyopneumothorax following CT-guided radiofrequency ablation for lung cancer with interstitial pneumonia2012

    • Author(s)
      Okuma T, Tsuji T, Sakamamo T, et al
    • Journal Title

      Acta radiolo Sh Rep

      Volume: 1 Pages: 19-19

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Radiofrequency ablation of liver tumors in combination with local OK-432 injection prolongs survival and suppresses distant tumor growth in the rabbit model with intra and extrahepati VX2 tumors

    • Author(s)
      Kageyama K, Yamamoto A, Hamamoto S, Okuma T et. al.
    • Journal Title

      Cardiovasc interv radiol

      Volume: (In press)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] The Utility of Expiratory Thin-Section CT for Fibrotic Interstitial Pneumonia2012

    • Author(s)
      Tomohisa Okuma
    • Organizer
      Radiological society of north america
    • Place of Presentation
      McCormic Place, Chicago, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] 特異な進展形式を示した悪性中皮腫の1例2012

    • Author(s)
      大隈智尚
    • Organizer
      日本肺癌学会総会
    • Place of Presentation
      岡山コンベンションセンター
    • Related Report
      2012 Annual Research Report
  • [Presentation] RFA in Combination with Local Injection of ...2011

    • Author(s)
      S hamamoto, T Okuma et al.
    • Organizer
      北米放射線学会
    • Place of Presentation
      アメリカ シカゴ市
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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