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Basic research to embolization uterie artery using NBCA Lipiodol in perinatal bleeding

Research Project

Project/Area Number 23791444
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionKeio University

Principal Investigator

HOSOKAWA takahiro  慶應義塾大学, 医学部, 共同研究員 (20383854)

Research Collaborator INOUE Masanori  慶應義塾大学, 医学部, 共同研究員 (30338157)
UENO Akihisa  慶應義塾大学, 医学研究科, 大学院生 (80348755)
NAKATSUKA Seishi  慶應義塾大学, 医学部, 講師 (50188984)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
KeywordsNBCA / 偽妊娠豚子宮動脈塞栓 / 子宮動脈塞栓 / 豚偽妊娠子宮動脈塞栓 / 周産期出血
Research Abstract

Perinatal bleeding is a condition that threatens the life of patient.Now, embolization from the uterine artery has been attempted. And embolization using NBCA has also increased.But there were a few pathological basic research after using NBCA.
First, the uterine artery of two pigs was embolization using lipiodol and NBCA. Hysterectomy was performed to examine the extent of the NBCA and Lipiodol, and to observe in pathologic evaluation. The distribution of embolization material evaluated by soft X-ray was almost concordant by pathological evaluation. Second, after embolization using NBCA, two pigs were fed two weeks. Then angiography was performed to evaluate in the extent of embolic material. Then, we examined pathologically extent of embolic material, the effects on endometrium. In two weeks, it appeared that the degree of residual intravascular embolic material had different concentrations, but not change the extent of the range of distribution.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (2 results)

All 2013

All Presentation (2 results)

  • [Presentation] 豚偽妊娠子宮動脈に対するNBCAを用いた塞栓術後の塞栓範囲の検討、軟X線と病理組織標本の対比を中心に2013

    • Author(s)
      細川 崇洋
    • Organizer
      第49回日本医学放射線学会秋季臨床大会
    • Place of Presentation
      名古屋国際会議場
    • Related Report
      2013 Final Research Report
  • [Presentation] 豚偽妊娠子宮動脈に対するNBCAを用いた塞栓術後の塞栓範囲の検討,軟X線と病理組織標本の対比を中心に2013

    • Author(s)
      細川崇洋
    • Organizer
      日本医学放射線学会秋季臨床大会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Related Report
      2013 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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