Initial investigation of predicting radiosensitivity and optimal dose fractionation against glioblastoma
Project/Area Number |
23791445
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Radiation science
|
Research Institution | Keio University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 膠芽腫 / 低分割放射線治療 / 悪性膠芽腫 |
Research Abstract |
Various single dose irradiation was performed to several malignantglioma cell lines to obtain survival curves. Radiation sensitivity was significantly high in LN 229 cell line (wild type) by high dose irradiation exceeding 8Gy. Gene mutation of PTEN and p
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Report
(3 results)
Research Products
(4 results)