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Development of a dose calculation method and a treatment planning system for radiotherapy based on the Boltzmann transport equation

Research Project

Project/Area Number 23791449
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionJuntendo University

Principal Investigator

SUGIMOTO Satoru  順天堂大学, 医学(系)研究科(研究院), 助教 (00373316)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords放射線治療 / 線量計算 / 線量分布最適化 / 線量不確かさ / 小照射野 / モンテカルロ計算 / ボルツマン方程式 / 動体追尾照射 / 4次元治療計画 / 治療計画システム / 吸収線量計算 / コーン・ビーム・コンピュータ・トモグラフィ / モンテカルロ法 / 電子線 / 不確実性 / VMAT / 最適化
Research Abstract

The purpose of the project was to develop a fast and accurate dose calculation code for the state-of-the-art radiotherapy of cancer and a treatment planning optimization system based on it. While we could not complete the development of the dose calculation code, we revealed the necessary conditions which should be satisfied by the new dose calculation code by investigating small fields, where the uncertainty of usual dose calculation methods can be large. As for the optimization for treatment planning, we developed the method of the evaluation of dose uncertainty, which is necessary for the minimization of dose uncertainty. We also developed the dose calculation method for moving tumors, which can be used for the optimization considering tumor motions.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (26 results)

All 2014 2013 2012 2011

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (23 results)

  • [Journal Article] The dosimetric impact of respiratory breast movement and daily setup error on tangential whole breast irradiation using conventional wedge, field-in-field and irregular surface compensator techniques2013

    • Author(s)
      Tomohisa Furuya, Satoru Sugimoto, Chie Kurokawa, Shuichi Ozawa, Kumiko Karasawa, Keisuke Sasai
    • Journal Title

      Journal of Radiation Research

      Volume: Vol. 54 Issue: 1 Pages: 157-165

    • DOI

      10.1093/jrr/rrs064

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Comparison of total MU and segment areas in VMAT and step-and-shoot IMRT plans.2013

    • Author(s)
      Kawashima M
    • Journal Title

      Radiol Phys Technol.

      Volume: 6(1) Issue: 1 Pages: 14-20

    • DOI

      10.1007/s12194-012-0164-3

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Comparison of hypofractionated and conventionally fractionated whole-breast irradiation for early breast cancer patients: a single-institute study of 1,098 patients2013

    • Author(s)
      Kumiko Karasawa
    • Journal Title

      Breast Cancer

      Volume: - Issue: 4 Pages: 402-408

    • DOI

      10.1007/s12282-012-0406-6

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] Dose-uncertaintyモデルを用いた前立腺VMATにおける内在的な線量不確かさの評価2014

    • Author(s)
      井上達也、杉本聡、堀川彌太郎、深田恭平、礒邉哲、伊藤佳菜、笹井啓資
    • Organizer
      第107回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2013 Annual Research Report
  • [Presentation] モンテカルロ計算コードEGSnrcとRICCを用いた大規模並列計算による全身照射の線量 評価について2014

    • Author(s)
      深田恭平、杉本聡、黒河千恵、井上達也、笹井啓資
    • Organizer
      第107回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dose Calculation Method for Dynamic Tumor Tracking Using a Gimbal-Mounted Linac2014

    • Author(s)
      S. Sugimoto, S. Utsunomiya, K. Ebe, T. Inoue, C. Kurokawa, K. Usui, K. Sasai
    • Organizer
      2014 AAPM Annual Meeting
    • Place of Presentation
      Austin, Texas, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] 治療計画システムPLanUNC上でのVero 4DRTのコミッショニングの検討2013

    • Author(s)
      杉本聡、井上達也、馬場竜太、荻原義貞、徳山克一、江部和勇
    • Organizer
      第106回日本医学物理学会学術大会
    • Place of Presentation
      大阪大学コンベンションセンター
    • Related Report
      2013 Final Research Report
  • [Presentation] Evaluation of inherent dose-uncertainty for VMAT using a dose uncertainty model2013

    • Author(s)
      Tatsuya Inoue, Satoru Sugimoto, Yataro Horikawa, Chie Kurokawa, Kyohei Fukata, Akira Isobe, Kana Ito, Keisuke Sasai
    • Organizer
      2013 AAPM Annual Meeting
    • Place of Presentation
      Indianapolis, Indiana, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] 動体追尾リニアックに搭載されたコーンビームCTの4次元再構成の検討2013

    • Author(s)
      杉本聡、芳賀昭弘、馬場竜太、山岸隆宏、高頭浩正、江部和勇
    • Organizer
      第105回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2013 Annual Research Report
  • [Presentation] Evaluation of Inherent Dose-Uncertainty for VMAT Using a Dose-Uncertainty Model2013

    • Author(s)
      T. Inoue, S. Sugimoto, Y. Horikawa, C. Kurokawa, K. Fukata, A. Isobe, K. Ito, K. Sasai
    • Organizer
      2013 AAPM Annual Meeting
    • Place of Presentation
      Indianapolis, Indiana, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Study of the Accuracy of the Dynamic Tracking System Using Radiographic Films2013

    • Author(s)
      T. Yamagishi, S. Sugimoto, R. Baba, H. Takato, T. Okumura, S. Takahashi, Y. Ogihara, S. Ozawa, K. Ebe
    • Organizer
      2013 AAPM Annual Meeting
    • Place of Presentation
      Indianapolis, Indiana, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] 治療計画システムPLanUNC上でのVero 4DRTのコミッショニングの検討2013

    • Author(s)
      杉本聡、井上達也、馬場竜太、荻原義貞、徳山克一、江部和勇
    • Organizer
      第105回日本医学物理学会学術大会
    • Place of Presentation
      大阪大学コンベンションセンター
    • Related Report
      2013 Annual Research Report
  • [Presentation] モンテカルロシミュレーションによる全身照射における吸収線量の評価2013

    • Author(s)
      深田恭平
    • Organizer
      日本物理学会第68回年次大会
    • Place of Presentation
      広島大学東広島キャンパス
    • Related Report
      2012 Research-status Report
  • [Presentation] 小照射野における検出器応答の検出部分体積・材質依存性のモンテカルロ計算による評価2012

    • Author(s)
      杉本聡、深田恭平、井上達也、黒河千恵、笹井啓資
    • Organizer
      第104回日本医学物理学会学術大会
    • Place of Presentation
      つくば国際会議場
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] Study of restricted mass stopping power ratio in small electron tube fields2012

    • Author(s)
      Satoru Sugimoto, Shuichi Ozawa, Hiromasa Takatou, Katsuichi Tokuyama, Hirotaka Maruyama, Takahiro Yamagishi, Ryuta Baba, Kazuyu Ebe, Keisuke Sasai
    • Organizer
      2012 AAPM Annual Meeting
    • Place of Presentation
      Charlotte, North Carolina, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] モンテカルロ線量計算の高速化に向けたHadoopによる分散環境の実践効果2012

    • Author(s)
      市村友寛、杉本聡、深田恭平、小澤修一、唐澤久美子、笹井啓資
    • Organizer
      第103回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] Study of Restricted Mass Stopping Power Ratio in Small Electron Tube Fields2012

    • Author(s)
      Satoru Sugimoto
    • Organizer
      2012 AAPM Annual Meeting
    • Place of Presentation
      Charlotte, North Carolina, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Evaluation of the Energy Dependence of Gafchromic EBT3 Film for Electron Beams2012

    • Author(s)
      Tatsuya Inoue
    • Organizer
      2012 AAPM Annual Meeting
    • Place of Presentation
      Charlotte, North Carolina, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] ガフクロミック EBT3 フィルムの X 線および電子線に対するエネルギー依存性の検証2012

    • Author(s)
      井上達也
    • Organizer
      第104回日本医学物理学会学術大会
    • Place of Presentation
      つくば国際会議場
    • Related Report
      2012 Research-status Report
  • [Presentation] A New Method of Total Body Irradiation Using a Field-in-Field Technique2012

    • Author(s)
      Hideo Yamamoto
    • Organizer
      ASTRO's 54th Annual Meeting
    • Place of Presentation
      Boston, Massachusetts, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Electronic Tissue Compensation を用いた乳房照射における心臓線量低減方法の検討2012

    • Author(s)
      礒邉哲
    • Organizer
      日本放射線腫瘍学会第25回学術大会
    • Place of Presentation
      東京国際フォーラム
    • Related Report
      2012 Research-status Report
  • [Presentation] kV CBCTにおける画質および線量の定量的評価に関する基礎検討2012

    • Author(s)
      丸山裕崇
    • Organizer
      日本放射線技術学会第68回総会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Research-status Report
  • [Presentation] Electronic tissue Compensationを用いた乳房照射のプラン検証方法の検討2012

    • Author(s)
      石杉沙織
    • Organizer
      第40回日本放射線技術学会
    • Place of Presentation
      タワーホール船堀
    • Related Report
      2012 Research-status Report
  • [Presentation] モンテカルロ治療計画線量計算におけるMean Varianceの最適化2012

    • Author(s)
      馬場竜太
    • Organizer
      第40回日本放射線技術学会
    • Place of Presentation
      タワーホール船堀
    • Related Report
      2012 Research-status Report
  • [Presentation] ジンバル式動体追尾照射の機械的追尾精度に関する基礎的検討2012

    • Author(s)
      山岸隆宏
    • Organizer
      第40回日本放射線技術学会
    • Place of Presentation
      タワーホール船堀
    • Related Report
      2012 Research-status Report
  • [Presentation] Monte Carlo calculation of mean electron energies in small circular electron fields at 45 degree incident angle2011

    • Author(s)
      Satoru Sugimoto, Shuichi Ozawa, Hiromasa Takatou, Katsuichi Tokuyama, Hirotaka Maruyama, Takahiro Yamagishi, Ryuta Baba, Kazuyu Ebe
    • Organizer
      the 6th Japan-Korea Joint Meeting on Medical Physics and the 11th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Fukuoka
    • Related Report
      2013 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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