Establishment of novel targeted therapy by inhibition of Notch signaling pathway in biliary tract cancer
| Project/Area Number |
23791514
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Digestive surgery
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
|---|
| Keywords | Notch / 癌幹細胞様細胞 / 胆管癌 |
|---|
| Research Abstract |
Although Notch signaling pathway is related to various malignancies, it is unclear whether it influences cancer of the biliary tract. In the present study, it was clarified that expression of Notch signaling pathway proteins in immunohistochemistry was seen in some resected cases with extrahepatic cholangiocarcinoma. The results of this study suggest influence of Notch signaling on extrahepatic cholangiocarcinoma.
|
Report
(4 results)
Research Products
(4 results)
