| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
We found some genes regarding as niche of cancer stem cell by using oligomicroarray with laser micro dissection method. (1) One of above genes, which concerns cell cycle, was evaluated the expression and function and associated with invasion of tumor, lymphatic invasion, clinical stage, distant metastasis, and prognosis. (2) We extract Glut-1 which is regarding glucose metabolism, and evaluated the expression of the cell membrane of tumor cell. After we consider the result of PET-CT which is thediagnostic modality using glucose uptake into the tumor cell, we investigated that Glut-1expression has correlate with FDG accumulation. Finally, we submitted this result to Annals of Surgical Oncology and they accepted as follows.
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