Integration of diffusion tensor tractography into stereotactic radiosurgery

• Project/Area Number: 23791586
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Cerebral neurosurgery
• Research Institution: Saitama Medical University
• Principal Investigator: KOGA Tomoyuki 埼玉医科大学, 医学部, 助教 (40456124)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 定位放射線治療 / 脳白質線維画像 / 脳白質繊維 / トラクトグラフィ / 拡散テンソル / 白質線維 / ガンマナイフ

Research Abstract

Diffusion tensor tractography was integrated into stereotactic radiosurgery. Tractography integrated treatment was performed for 71 among 144 patients. In a case control study, motor complication after treatment was significantly reduced in 24 patients with lesions close to the corticospinal tract who were treated by tractography integrated procedeure compared with 28 patients with similar lesions who were treated without use of tractography

Research Products

• [Journal Article] Radiosurgery for brainstem arteriovenous malformation. (2013)
  • Author(s): Maruyama K, Koga T, Niranjan A, Kondziolka D, Flickinger JC, Lunsford D
  • Journal Title: Progress in Neurological Surgery Volume: 27 Pages: 67-72
  • Peer Reviewed
• [Journal Article] Radiosurgery for brainstem arteriovenous malformation (2013)
  • Author(s): Maruyama K
  • Journal Title: Progress in Neurological Surgery Volume: 27 Pages: 67-72
  • DOI: 10.1159/000341639
  • ISBN: 9783805596190, 9783805596206
  • Peer Reviewed
• [Journal Article] Efficacy and limitations of stereotactic radiosurgeryin the treatment of glioblastoma. (2012)
  • Author(s): Koga T, Saito N
  • Journal Title: Neurol Med Chir (Tokyo) Volume: 52 Pages: 548-52
  • Peer Reviewed
• [Journal Article] Extended field stereotactic radiosurgery for recurrent glioblastoma (2012)
  • Author(s): Koga T, Maruyama K, Tanaka M, Ino Y, Saito N, Nakagawa K, Shibahara J, Todo T
  • Journal Title: Cancer Volume: 118 Pages: 4193-200
  • Peer Reviewed
• [Journal Article] Role of stereotactic radiosurgery in the treatment of high-grade cerebral arteriovenous malformation (2012)
  • Author(s): Hanakita S,Koga T, Shin M, Shojima M, Igaki H, Saito N
  • Journal Title: Neurol Med Chir (Tokyo) Volume: 52 Pages: 845-851
  • NAID: 10031131525
  • Peer Reviewed
• [Journal Article] Role of gamma knife surgery in treatment of intracranial dural arteriovenous fistula (2012)
  • Author(s): Hanakita S, Koga T, Shin M, Shojima M, Igaki H, Saito N.
  • Journal Title: J Neurosurg Volume: 117 Pages: 158-63
  • Peer Reviewed
• [Journal Article] Delayed complication after gamma knife radiosurgery for mesial temporal lobe epilepsy. (2012)
  • Author(s): Usami K, Kawai K, Koga T, ShinM, Kurita H, Suzuki I, Saito N.
  • Journal Title: J Neurosurg Pages: 1221-5
  • Peer Reviewed
• [Journal Article] Integration of corticospinal tractography reduces motor complication after radiosurgery. (2012)
  • Author(s): Koga T, Shin M, Maruyama K, Kamada K, Ota T, Itoh D, Kunii N, Ino K, Aoki S, Masutani Y, Igaki H, Onoe T, Saito N.
  • Journal Title: Int J Radiat Oncol Biol Phys Volume: 83 Pages: 129-133
  • Peer Reviewed
• [Journal Article] Outcomes of diffusion-tensor tractography integrated stereotactic radiosurgery. (2012)
  • Author(s): Koga T, Maruyama K, Kamada K, Ota T, Shin M, Itoh D, Kunii N, Ino K, Terahara A, Aoki S, Masutani Y, Saito N
  • Journal Title: Int J Radiat Oncol Biol Phys Volume: 82 Pages: 799-802
  • Peer Reviewed
• [Journal Article] Efficacy and limitations of stereotactic radiosurgery in the treatment of glioblastoma (2012)
  • Author(s): Koga T
  • Journal Title: Neurol Med Chir (Tokyo) Volume: 52 Pages: 548-552
  • NAID: 10030694550
  • Peer Reviewed
• [Journal Article] Role of Gamma Knife surgery in the treatment of intracranial dural arteriovenous fistulas. (2012)
  • Author(s): Hanakita S, Koga T, Shin M, Shojima M, Igaki H, Saito N.
  • Journal Title: J Neurosurg Volume: 117 Suppl Issue: Special_Suppl Pages: 158
  • DOI: 10.3171/2012.7.gks12967
  • Peer Reviewed
• [Journal Article] Delayed complication after Gamma Knife surgery for mesial temporal lobe epilepsy: Clinical article (2012)
  • Author(s): Usami K, Kawai K, Koga T, Shin M, KuritaH, Suzuki I, Saito N
  • Journal Title: J Neu-rosurg Volume: 116 Issue: 6 Pages: 1221
  • DOI: 10.3171/2012.2.jns111296
  • Peer Reviewed
• [Journal Article] Outcomes of diffusion tensor tractography-integrated stereotactic radiosurgery (2012)
  • Author(s): Koga T, Maruyama K, et.al
  • Journal Title: Int J Radiat Oncol Biol Phys Volume: 82 Issue: 2 Pages: 799
  • DOI: 10.1016/j.ijrobp.2010.11.046
  • Peer Reviewed
• [Journal Article] Outcomes of diffusion-tensor tractography integrated stereotactic radiosurgery (2012)
  • Author(s): Koga T, Maruyama K, Kamada K, Ota T, Shin M, Itoh D, Kunii N, Ino K, Terahara A, Aoki S, Masutani Y, Saito N
  • Journal Title: International journal of radiation oncology, biology, and physics Volume: 82 Pages: 799-802
  • Peer Reviewed
• [Journal Article] Contribution of technological progress, inter-operator difference and experience of operators in gamma knife radiosurgery for arteriovenous malformation (2011)
  • Author(s): Koga T, Shin M, Maruyama K, Kurita H, Kawamoto S, Saito N
  • Journal Title: Acta Neurochir (Wien) Volume: 153 Pages: 879-882
  • Peer Reviewed
• [Journal Article] Outcomes of radiosurgery for brain stem arteriovenous malformations (2011)
  • Author(s): Koga T, Shin M, Terahara A, Saito N.
  • Journal Title: Neurosurgery Volume: 69 Pages: 45-52
  • Peer Reviewed
• [Journal Article] Extended field stereotactic radiosurgery for recurrent glioblastoma (2011)
  • Author(s): Koga T, Maruyama K, Tanaka M, Ino Y, Saito N, Nakagawa K, Shibahara J, Todo T
  • Journal Title: Cancer Volume: 118 Issue: 17 Pages: 4193
  • DOI: 10.1002/cncr.27372
  • Peer Reviewed
• [Journal Article] Integration of corticospinal tractography reduces motor complications after radiosurgery (2011)
  • Author(s): Koga T, Shin M, Maruyama K, Kamada K, Ota T, Itoh D, Kunii N, Ino K, Aoki S, Masutani Y, Igaki H, Onoe T, Saito N
  • Journal Title: Int J Radiat Oncol Biol Phys Volume: 83 Issue: 1 Pages: 129
  • DOI: 10.1016/j.ijrobp.2011.05.036
  • Peer Reviewed
• [Journal Article] 脳動静脈奇形のガンマナイフ治療 (2011)
  • Author(s): 甲賀智之
  • Journal Title: Clinical Neuroscience Volume: 29 Pages: 1172-1174
• [Journal Article] Extended field stereotactic radiosurgery for recurrent glioblastoma (2011)
  • Author(s): Koga T, Maruyama K, Tanaka M, Ino Y, Saito N, Nakagawa K, Shibahara J, Todo T.
  • Journal Title: Cancer Volume: -
  • Peer Reviewed
• [Journal Article] 脳動静脈奇形に対するガンマナイフ治療 (2011)
  • Author(s): 甲賀智之
  • Journal Title: Annual Review 神経 2011 Volume: - Pages: 187-193
• [Presentation] 再発神経膠芽腫の長期腫瘍制御をめざした定位放射線治療の照射野拡大の効果(特別シンポジウム) (2011)
  • Author(s): 甲賀智之,藤堂具紀,花北俊哉,辛正廣,丸山啓介,武笠晃丈,齊藤邦昭,斉藤延人
  • Organizer: 社団法人日本脳神経外科学会総会第70回学術総会
  • Place of Presentation: 横浜
  • Year and Date: 2011-10-13
• [Presentation] High-grade AVM の治療における定位放射線治療の役割(シンポジウム) (2011)
  • Author(s): 甲賀智之,辛正廣,丸山啓介,花北俊哉,井垣浩,斉藤延人
  • Organizer: 第40回日本脳卒中の外科学会
  • Place of Presentation: 京都
  • Year and Date: 2011-07-31
• [Presentation] 拡散テンソルトラクトグラフィ合成によるガンマナイフ治療に伴う合併症の予防(シンポジウム) (2011)
  • Author(s): 甲賀智之,辛正廣,丸山啓介,花北俊哉,井垣浩,斉藤延人
  • Organizer: 第20回日本定位放射線治療学会
  • Place of Presentation: 名古屋
  • Year and Date: 2011-07-29
• [Presentation] 頭蓋底髄膜腫治療における定位放射線治療の役割 (2011)
  • Author(s): 甲賀智之,辛正廣,花北俊哉,斉藤延人
  • Organizer: 第23回日本頭蓋底外科学会
  • Place of Presentation: 大阪
  • Year and Date: 2011-06-17
• [Presentation] Comparison of outcomes after brain radiosurgery with and without use of diffusion-tensor tractography. (2011)
  • Author(s): Koga T, Shin M, Maruyama K, Hanakita S, Kunii N, Ino K, Mastani Y, Saito N
  • Organizer: 10th Biennial Conbress and Exhibition of the International Stereotactic Radiosurgery Society
  • Place of Presentation: Paris, France
  • Year and Date: 2011-05-11
• [Presentation] Comparison of outcomes after brain radiosurgery with and without use of diffusion-tensor tractography (2011)
  • Author(s): Koga T, Shin M, Maruyama K, Hanakita S, Kunii N, Ino K, Mastani Y, Saito N
  • Organizer: 10th Biennial Conbress and Exhibition of the International Stereotactic Radiosurgery Society
  • Place of Presentation: Paris, France
• [Presentation] 拡散テンソルトラクトグラフィ合成によるガンマナイフ治療に伴う合併症の予防 (2011)
  • Author(s): 甲賀智之，辛正廣，丸山啓介，花北俊哉，井垣浩，斉藤延人
  • Organizer: 第20回日本定位放射線治療学会
  • Place of Presentation: 名古屋
• [Presentation] High-grade AVM の治療における定位放射線治療の役割 (2011)
  • Author(s): 甲賀智之，辛正廣，丸山啓介，花北俊哉，井垣浩，斉藤延人
  • Organizer: 第40回日本脳卒中の外科学会
  • Place of Presentation: 京都
• [Presentation] 再発神経膠芽腫の長期腫瘍制御をめざした定位放射線治療の照射野拡大の効果 (2011)
  • Author(s): 甲賀智之，藤堂具紀，花北俊哉，辛正廣，丸山啓介，武笠晃丈，齊藤邦昭，斉藤延人
  • Organizer: 社団法人日本脳神経外科学会総会第70回学術総会
  • Place of Presentation: 横浜
• [Book] Nobuhito Saito. Role of Neuroimaging in Brain Radiosurgery (2012)
  • Author(s): Tomoyuki Koga
  • Publisher: Neuroimaging - Clinical Applications
• [Book] Neuroimaging - Clinical Applications, pp129-144 (2012)
  • Author(s): Tomoyuki Koga
  • Total Pages: 16
  • Publisher: Role of Neuroimaging in Brain Radiosurgery