In vivo MR imaging of bone marrow cells in GBM
| Project/Area Number |
23791595
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 膠芽腫 / MRI / 造血幹細胞 / 分子イメージング |
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| Research Abstract |
We have developed MagA, which is an MR reporter gene, overexpressing transgenic mouse, and pursued the possibility of tracking bone marrow derived cells in the course of glioblastoma development by MRI. We were able to confirm that bone marrow cells from MagA transgenic mouse accumulate more iron than wild type mouse and that those cells showed hypo-intense signals under MRI observation.
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Report
(3 results)
Research Products
(41 results)
