| Project/Area Number |
23791600
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Osaka University |
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Principal Investigator |
YAMAMOTO Fukuko 大阪大学, 医学(系)研究科(研究院), 研究員 (30533799)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 小児悪性脳腫瘍 / 晩期障害 / 認知機能 / Diffusion Tensor Imaging / Quality of Life / Quality of life |
|---|
| Research Abstract |
Pleural cognitive function tests (WAIS-R, WISC-R) were performed for long-term survivors of pediatric medulloblastomas treated by reduced-dose craniospinal irradiation. Interval from onset to measurement was 3-7 years (average 4.75 years). Total IQ was 83.6 (95% CI, 73-94.2), verbal IQ (VIQ) was 94.4 (95% CI, 85.8-103) and performance IQ (PIQ) was 74.8 (95% CI, 62-87.6). PIQ was significantly lower than VIQ, especially at the point of processing speed and visual perception. PIQ was lower in cases with cerebellar ataxia and cranial nerve dysfunction. There is no important relationship between patients' age at diagnosis and IQ.
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