Molecular genetic analyses of bone and soft tissue tumors
Project/Area Number |
23791627
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Orthopaedic surgery
|
Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
KIMURA Ayako 東京医科歯科大学, 硬組織疾患ゲノムセンター, 特任助教 (30597232)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 骨軟部腫瘍 |
Research Abstract |
Genetic analysis was performed using human osteosarcoma samples, failed to detect any apparent genetic alterations. Using osteosarcoma cell line, we isolated the genes involving the development and progression of osteosarcoma. Overexpression and knockdown of the gene demonstrated its function in cell proliferation, migration and invasion.
|
Report
(4 results)
Research Products
(5 results)