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The Effect of Blood Glucose Levels onthe Shivering Threshold in Rabbits

Research Project

Project/Area Number 23791692
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Anesthesiology/Resuscitation studies
Research InstitutionUniversity of Yamanashi

Principal Investigator

MASAMUNE Taishi  山梨大学, 医学部附属病院, 助教 (40324199)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords周術期管理学 / 体温 / 血糖 / シバリング
Research Abstract

We evaluated the effect of blood glucose concentration on the shivering threshold in rabbits. The shivering threshold was linearly related to blood glucose concentration in rabbits. While shivering was the only thermoregulatory defense evaluated in this study, thresholds for vasoconstriction and sweating/panting usually change synchronously. To the extent that humans respond similarly, hyperglycemia may increased the sweating threshold and thus facilitate hyperthermia. And these data support the theory that hypoglycemia contributes to hypothermia, and that exertional hypothermia may result from concomitant hypoglycemia.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (5 results)

All 2012 2011 Other

All Presentation (4 results) Remarks (1 results)

  • [Presentation] 血糖値がシバリング閾値温度に与える影響(低血糖編)-ウサギでの研究-2012

    • Author(s)
      和田 啓一、正宗 大士、古藤田 眞和、上田 健太、鈴木 翔、松川 隆
    • Organizer
      日本麻酔科学科関東甲信越・東京支部第52回合同学術集会
    • Place of Presentation
      軽井沢プリンスホテル(長野県)
    • Year and Date
      2012-09-22
    • Related Report
      2012 Final Research Report
  • [Presentation] 血糖値がシバリング閾値温度に与える影響-ウサギでの研究-2011

    • Author(s)
      猪野 博史、正宗 大士、佐藤 宏明、岩下 博宣、奥山 克巳、松川 隆
    • Organizer
      日本麻酔科学会第58回学術集会
    • Place of Presentation
      神戸ポートピアホテル・神戸国際会議場(神戸市)
    • Year and Date
      2011-05-20
    • Related Report
      2012 Final Research Report
  • [Presentation] 血糖値がシバリング閾値温度に与える影響-ウサギでの研究-2011

    • Author(s)
      猪野博史 ほか
    • Organizer
      日本麻酔科学会第58回学術集会
    • Place of Presentation
      神戸ポートピアホテル・神戸国際会議場(神戸市)
    • Related Report
      2011 Research-status Report
  • [Presentation] 血糖値がシバリング閾値温度に与える影響(低血糖編)-ウサギでの研究-

    • Author(s)
      和田啓一 ほか
    • Organizer
      日本麻酔科学科関東甲信越・東京支部第52回合同学術集会
    • Place of Presentation
      軽井沢プリンスホテル(長野県)
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://y-anesth.jp/research/temperature/

    • Related Report
      2012 Final Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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