Microcirculation in sepsis: Relationship between intestinal and sublingual microcirculatory perfusion
| Project/Area Number |
23791713
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 敗血症性ショック / 腸管血流 / 舌血流 / 敗血症 / 腸管粘膜血流 / 腸型脂肪酸結合蛋白 / endotoxin activity assay |
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| Research Abstract |
In septic shock patients, enterocyte damage assessed by intestinal fatty acid-binding protein (I-FABP) is frequent. Plasma I-FABP concentration at admission to the ICU is significantly associated with APACHE II score, lactate, ischemic change of tongue and abdominal complication. Further study is needed to determine whether plasma I-FABP concentration is associated with mortality.
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Report
(4 results)
Research Products
(16 results)
