Research Project
Grant-in-Aid for Young Scientists (B)
We have investigated exocytotic release of ATP from urothelium, especially focusing on vesicular nucleotide transporter (VNUT). VNUT gene and protein was highly expressed in the epithelial layer of mouse bladder tissue and primary urothelial cell culture. The stretch-evoked ATP release was significantly reduced by the treatment of VNUT siRNA or several inhibitors of vesicular exocytosis. These findings suggest that VNUT plays an important role in stretch-elicited ATP release from urothelium.
All 2013 2012 2011 2010 Other
All Journal Article (6 results) (of which Peer Reviewed: 1 results) Presentation (24 results) Remarks (1 results)
新薬展望 2013
Volume: Vol. 49
診断と治療
Volume: 第100巻・第8号 Pages: 1379-1385
Progress in Medicine
Volume: Vol. 32 (No. 4) Pages: 37-42
Committee3 Cell Biology 「細胞生物学」.排尿障害プラクティス
Volume: Vol.19(1) Pages: 66-88
LUTS (Lower Urinary Tract Symptoms)
Volume: 2 Pages: 51-60
臨床検査
Volume: Vol.54(7) Pages: 726-730