Analysis of the role and the polymorphism of the oxidative stress related gene for the promotion of prostate carcinogenesis

• Project/Area Number: 23791779
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Urology
• Research Institution: Osaka City University
• Principal Investigator: IGUCHI Taro 大阪市立大学, 大学院・医学研究科, 講師 (80529206)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 腫瘍学 / 前立腺癌 / 遺伝子多型 / 酸化ストレス

Research Abstract

The predictive OR of MnSOD AA for significant versus insignificant cancers was 5.04 (sensitivity=0.58; positive predictive value=0.79) in men >70 years old. MnSOD polymorphism is strongly associated with the clinical significance of prostate canc

Research Products

• [Journal Article] Intermediate oncological outcomes of percutaneous radiofrequency ablation for small renal tumors: initial experience (2012)
  • Author(s): Nitta Y, Iguchi T, Nakatani T etc
  • Journal Title: Anticancer Res Volume: 32 Pages: 615-8
  • Peer Reviewed
• [Journal Article] Intermediate oncological outcomes of percutaneous radiofrequency ablation for small renal tumors: initial experience. (2012)
  • Author(s): Nitta Y
  • Journal Title: Anticancer Res Volume: 32 Pages: 615-618
  • Peer Reviewed
• [Journal Article] Intermediate oncological outcomes of percutaneous radiofrequency ablation for small renal tumors: initial experience. (2012)
  • Author(s): Yujiro Nitta
  • Journal Title: Anticancer Res. Volume: 32 Pages: 615-618
• [Presentation] The efficiency of second- line chemotherapy with gemcitabine and paclitaxel for advanced urothelial carcinoma resistant to cisplatinbased chemotherapy. (2013)
  • Author(s): Nishihara C, Iguchi T, Nakatani T etc
  • Organizer: American Urological Association Annual Meeting 2013
  • Place of Presentation: San Diego, CA USA
  • Year and Date: 2013-05-07
• [Presentation] The efficiency of second-line chemotherapy with gemcitabine and paclitaxel for advanced urothelial carcinoma resistant to cisplatin-based chemotherapy. (2013)
  • Author(s): Nishihara C
  • Organizer: AUA2013 Annual Meeting
  • Place of Presentation: San Diego Convention Center, San Diego, USA
• [Presentation] Prognostic Factor of Second Biopsy for Detection of Prostate Cancer. (2012)
  • Author(s): Nishihara C, Iguchi T, Nakatani T etc
  • Organizer: 32st Congress of the Societe Internationale d' Urologie
  • Place of Presentation: Fukuoka, Japan
  • Year and Date: 2012-10-02
• [Presentation] Chronic Kidney Disease after Urolithiasis Treated Successfully by Shock Wave Lithtripsy Is Strong Risk Factor for Cardiovascular Disease (2012)
  • Author(s): Iguchi T, Nakatani T etc.
  • Organizer: 32st Congress of the Societe Internationale d' Urologie
  • Place of Presentation: Fukuoka, Japan
  • Year and Date: 2012-10-01
• [Presentation] Chronic Kidney Disease after Urolithiasis Treated Successfully by Shock Wave Lithtripsy Is Strong Risk Factor for Cardiovascular Disease. (2012)
  • Author(s): Iguchi T
  • Organizer: 32st Congress of the Societe Internationale d'Urologie
  • Place of Presentation: Fukuoka International Congress Center, Fukuoka, Japan
• [Presentation] Prognostic Factor of Second Biopsy for Detection of Prostate Cancer. (2012)
  • Author(s): Nishihara C
  • Organizer: 32st Congress of the Societe Internationale d'Urologie
  • Place of Presentation: Fukuoka International Congress Center, Fukuoka, Japan
• [Presentation] Chronic Kidney Disease Associated With Shock Wave Lithotripsy of Renal calculi (2011)
  • Author(s): Taro Iguchi
  • Organizer: American Urological Association annual meeting 2011
  • Place of Presentation: Washington, D.C., USA
• [Presentation] A Case of intractable renal abscess successfully treated by radiofrequency ablation. (2011)
  • Author(s): Taro Iguchi
  • Organizer: The 29th World Congress of Endourology & SWL
  • Place of Presentation: Kyoto, Japan
• [Remarks] 大阪市立大学 大学院医学研究科 泌尿器病態学 研究グループ
  • URL: http://www.med.osaka-cu.ac.jp/urology/research-1.html