Establishment of the treatment strategy for the superficial and invasive bladder cancer cell using the bafilomycin
Project/Area Number |
23791784
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Urology
|
Research Institution | Keio University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | 癌 / 癌治療 / 膀胱癌 / 化学療法 / バフィロマイシン / 尿路上皮癌 / アポトーシス / 予後因子 / 動物モデル / 抗癌剤 |
Research Abstract |
The bafilomycin induced antitumor effect of bladder cancer cell lines through the inhibition of the Bcl-xL protein function. The Bcl-xL protein was presented at high frequency in the specimen of the upper urinary tract urothelial carcinoma and the high ex
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Report
(3 results)
Research Products
(5 results)