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Liposomal PTEN Gene Therapy in an Orthotopic Bladder Cancer Modeland Prevention of Tumor Invasion and Metastasis

Research Project

Project/Area Number 23791786
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Urology
Research InstitutionKeio University

Principal Investigator

MATSUMOTO Kazuhiro  慶應義塾大学, 医学部, 共同研究員 (80366153)

Research Collaborator KIKUCHI Eiji  慶應義塾大学, 医学部, 講師 (10286552)
MIYAJIMA Akira  慶應義塾大学, 医学部, 講師 (90245572)
OYA Mototsugu  慶應義塾大学, 医学部, 教授 (00213885)
Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
KeywordsPTEN / 遺伝子治療 / 免疫治療 / 筋層非浸潤性膀胱癌 / 膀胱癌 / マウス膀胱癌同所性モデル
Research Abstract

Efficient gene transfection of LacZ reporter plasmid to MBT2variant cells using a reagent GenePORTER3000 was confirmed with X-gal staining. In thesame way, we transfected PTEN plasmid to MBT2 variant cells, and observed high expressionof PTEN protein and

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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