Energy metabolism of seminiferous epithelium in spermatogenesis
| Project/Area Number |
23791793
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Urology
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| Research Institution | Fujita Health University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | アンドロロジー / 精子発生 / 脂肪酸代謝 / 栄養代謝 / 栄養学 / 細胞・組織 |
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| Research Abstract |
Seminiferous epithelium is the site of spermatogenesis and is a unique environment in energy metabolism because of its separation from the blood. Such characteristics may contribute to spermatogenesis in quality or quantity. Previous study shows that Sertoli cells that surround spermatogenic cells have less gene expression level of energy production pathways except glycolysis than liver, however, they can metabolize fatty acid as another energy source. Energy or metabolite by fatty acid oxidation of Sertoli cells may be important to spermatogenesis.
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Report
(3 results)
Research Products
(10 results)
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[Journal Article] Expression of 3β-hydroxysteroid dehydrogenase (hsd3b), star and ad4bp/sf-1 during gonadal development in medaka (Oryzias latipes)2012
Author(s)
Nakamoto, M., Fukasawa, M., Tanaka, S., Shimamori, K., Suzuki, A., Matsuda, M., Kobayashi, T., Nagahama, Y., Shibata, N.
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Journal Title
Gen Comp Endocrinol
Volume: 176
Issue: 2
Pages: 222-30
DOI
Related Report
Peer Reviewed
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