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Energy metabolism of seminiferous epithelium in spermatogenesis

Research Project

Project/Area Number 23791793
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Urology
Research InstitutionFujita Health University

Principal Investigator

FUKASAWA Motoaki  藤田保健衛生大学, 医学部, 助教 (70387728)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywordsアンドロロジー / 精子発生 / 脂肪酸代謝 / 栄養代謝 / 栄養学 / 細胞・組織
Research Abstract

Seminiferous epithelium is the site of spermatogenesis and is a unique environment in energy metabolism because of its separation from the blood. Such characteristics may contribute to spermatogenesis in quality or quantity. Previous study shows that Sertoli cells that surround spermatogenic cells have less gene expression level of energy production pathways except glycolysis than liver, however, they can metabolize fatty acid as another energy source. Energy or metabolite by fatty acid oxidation of Sertoli cells may be important to spermatogenesis.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (10 results)

All 2013 2012 2011 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (7 results) Remarks (2 results)

  • [Journal Article] Expression of 3β-hydroxysteroid dehydrogenase (hsd3b), star and ad4bp/sf-1 during gonadal development in medaka (Oryzias latipes)2012

    • Author(s)
      Nakamoto, M., Fukasawa, M., Tanaka, S., Shimamori, K., Suzuki, A., Matsuda, M., Kobayashi, T., Nagahama, Y., Shibata, N.
    • Journal Title

      Gen Comp Endocrinol

      Volume: 176 Issue: 2 Pages: 222-30

    • DOI

      10.1016/j.ygcen.2012.01.019

    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Presentation] ミトコンドリア脂肪酸β酸化系酵素の初代培養細胞における免疫組織化学と in vitro probe assay による解析2013

    • Author(s)
      厚沢季美江
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川県高松市
    • Year and Date
      2013-03-28
    • Related Report
      2012 Final Research Report
  • [Presentation] ミトコンドリア脂肪酸β酸化系酵素の初代培養細胞における免疫組織化学とin vitro probe assayによる解析2013

    • Author(s)
      厚沢季美江、松澤綾美、深澤元晶、古居みどり、山口清次、臼田信光
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川県高松市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 培養Sertoli細胞の免疫組織化学2012

    • Author(s)
      深澤元晶
    • Organizer
      第72回日本解剖学会中部支部学術集会
    • Place of Presentation
      岐阜県岐阜市
    • Year and Date
      2012-10-13
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] ミトコンドリアの組織化学-精巣-2012

    • Author(s)
      深澤元晶
    • Organizer
      第117回日本解剖学会総会・学術集会シンポジウム「新しく開かれるミトコンドリアの構造と機能」
    • Place of Presentation
      山梨県甲府市
    • Year and Date
      2012-03-26
    • Related Report
      2012 Final Research Report
  • [Presentation] ミトコンドリアの組織化学と臓器差 -精巣-2012

    • Author(s)
      深澤元晶
    • Organizer
      第117回 日本解剖学会総会・学術集会 シンポジウム「新しく開かれるミトコンドリアの構造と機能」(招待講演)
    • Place of Presentation
      山梨県甲府市
    • Related Report
      2011 Research-status Report
  • [Presentation] 細胞内微小環境栄養学:精巣におけるミトコンドリア脂肪酸β酸化系酵素の免疫組織化学的局在2011

    • Author(s)
      深澤元晶
    • Organizer
      第71回日本解剖学会中部支部学術集会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2011-10-16
    • Related Report
      2012 Final Research Report
  • [Presentation] 細胞内微小環境栄養学:精巣におけるミトコンドリア脂肪酸β酸化系酵素の免疫組織化学的局在2011

    • Author(s)
      深澤元晶
    • Organizer
      第71回 日本解剖学会中部支部学術集会
    • Place of Presentation
      愛知県名古屋市
    • Related Report
      2011 Research-status Report
  • [Remarks] 藤田保健衛生大学医学部解剖学II

    • URL

      http://www.fujita-hu.ac.jp/~hnagashi/KDB/open/100012.html

    • Related Report
      2012 Final Research Report
  • [Remarks] 藤田保健衛生大学医学部 解剖学II

    • URL

      http://www.fujita-hu.ac.jp/~hnagashi/KDB/open/100012.html

    • Related Report
      2012 Annual Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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