Micro RNA analysis in orooraryngeal carcinoma

• Project/Area Number: 23791867
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Otorhinolaryngology
• Research Institution: Hokkaido University
• Principal Investigator: MIZUMACHI Takatsugu 北海道大学, 大学病院, 助教 (00507577)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 頭頸部癌 / 中咽頭癌 / ＨＰＶ / HPV / 化学放射線療法 / p16 / マイクロＲＮＡ / 個別化治療 / geldanamycin / HSP90 / 遺伝子発現

Research Abstract

We performed a retrospective analysis of the association between tumour HPV status and the demographic and clinicopathological parameters of 71 patients with oropharyngeal squamous cell carcinoma. Of the 71 patients, 23 were HPV-positive. Kaplan-Meier survival analysis showed improved overall survival rates in patients with HPV-positive tumours compared with HPV-negative tumours. Of the 45 patients received chemoradiotherapy, HPV-positive patients experienced better overall survival than HPV-negative patients. We performed a retrospective analysis of the association between p16 expression and HPV status. Of the 91 patients, 29 were HPV-positive and 31 were p16-positive. The 3-year overall survival rates were 82.2% in the p16-positive subgroup and 65.1% in the p16-negative subgroup. Our results showed that the patients with HPV-/p16+ had poor prognosis as compared with the patients with HPV+/p16+, therefore p16 IHC alone may not be a perfect surrogate marker for HPV infection.

Research Products

• [Journal Article] Improved survival of Japanese patients with human papillomavirus-positive oropharyngeal squamous cell carcinoma (2013)
  • Author(s): Mizumachi T, Kano S, Sakashita T, Hatakeyama H, Suzuki S, Homma A, Oridate N, Fukuda S
  • Journal Title: Int J Clin Oncol Volume: 2013 Pages: 824-8
  • Peer Reviewed
• [Journal Article] Prognostic value of cyclin D1 expression in tumor-free surgical margins in head and neck squamous cell carcinomas (2013)
  • Author(s): Sakashita T, Homma A, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Oridate N, Fukuda S
  • Journal Title: Acta Otolaryngol Volume: 133 Pages: 984-91
  • NAID: 120005476151
  • Peer Reviewed
• [Journal Article] Nasal manifestations of immunoglobulin G4-related disease (2013)
  • Author(s): Suzuki M, Nakamaru Y, Akazawa S, Mizumachi T, Maeda M, Takagi D, Hatanaka KC, Fukuda S
  • Journal Title: Laryngoscope Volume: 123 Pages: 829-34
  • Peer Reviewed
• [Journal Article] Regional control after concomitant chemoradiotherapy without planned neck dissection in node-positive head and neck squamous cell carcinomas (2013)
  • Author(s): Sakashita T, Homma A, Oridate N, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S
  • Journal Title: Auris Nasus Larynx Volume: 40 Pages: 211-5
  • NAID: 120005228702
  • Peer Reviewed
• [Journal Article] 中咽頭癌症例におけるHPV感染と転移リンパ節の検討 (2013)
  • Author(s): 水町貴諭,加納里志,本間明宏,折舘伸彦,福田諭
  • Journal Title: 口咽科 Volume: 26 Pages: 161-6
  • NAID: 10031183783
  • Peer Reviewed
• [Journal Article] 喉頭癌T3症例の治療成績の検討 (2013)
  • Author(s): 水町貴諭,折舘伸彦,本間明宏,坂下智博,加納里志,畠山博充,鈴木清護,福田諭
  • Journal Title: 頭頸部外科 Volume: 22 Pages: 317-21
  • NAID: 10031170514
  • Peer Reviewed
• [Journal Article] Prognostic value of cyclin D1 expression in tumor-free surgical margins in head and neck squamous cell carcinomas. (2013)
  • Author(s): Sakashita T, Homma A, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Oridate N, Fukuda S
  • Journal Title: Acta Otolaryngol Volume: 133 Issue: 9 Pages: 984-981
  • DOI: 10.3109/00016489.2013.795287
  • NAID: 120005476151
  • Peer Reviewed
• [Journal Article] Nasal manifestations of immunoglobulin G4-related disease. (2013)
  • Author(s): Suzuki M, Nakamaru Y, Akazawa S, Mizumachi T, Maeda M, Takagi D, Hatanaka KC, Fukuda S
  • Journal Title: Laryngoscope Volume: 123 Issue: 4 Pages: 829-834
  • DOI: 10.1002/lary.23792
  • Peer Reviewed
• [Journal Article] Superselective intra-arterial cisplatin infusion and concomitant radiotherapy for maxillary sinus cancer. (2013)
  • Author(s): Homma A, Sakashita T, Yoshida D, Onimaru R, Tsuchiya K, Suzuki F, Yasuda K, Hatakeyama H, Furusawa J, Mizumachi T, Kano S, Inamura N, Taki S, Shirato H, Fukuda S.
  • Journal Title: Br J Cancer Volume: 109 Issue: 12 Pages: 2980-2986
  • DOI: 10.1038/bjc.2013.663
  • NAID: 120005438253
  • Peer Reviewed
• [Journal Article] 中咽頭癌症例におけるHPV感染と転移リンパ節の検討 (2013)
  • Author(s): 水町貴諭, 加納里志, 本間明宏, 折舘伸彦, 福田 諭
  • Journal Title: 口咽科 Volume: 26 Pages: 317-321
  • NAID: 10031183783
  • Peer Reviewed
• [Journal Article] 喉頭癌T3症例の治療成績の検討 (2013)
  • Author(s): 水町貴諭, 折舘伸彦, 本間明宏, 坂下智博, 加納里志, 畠山博充, 鈴木清護, 福田 諭: 喉頭癌T3症例の治療成績の検討
  • Journal Title: 頭頸部外科 Volume: 22 Pages: 317-321
  • NAID: 10031170514
  • Peer Reviewed
• [Journal Article] 中咽頭扁平上皮癌症例におけるHPV感染とp16の発現に関する検討 (2013)
  • Author(s): 水町 貴諭, 畠山 博充, 加納 里志, 坂下 智博, 鈴木 清護, 本間 明宏, 折舘 伸彦, 福田 諭
  • Journal Title: 頭頸部癌 Volume: 39 Pages: 334-338
  • NAID: 130004510174
  • Peer Reviewed
• [Journal Article] Platinum concentration in sentinel lymph nodes after preoperative intra-arterial cisplatin chemotherapy targeting primary tongue cancer (2012)
  • Author(s): Sakashita T, Homma A, Oridate N, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Yoshida D, Fujima N, Fukuda S
  • Journal Title: Acta Otolaryngol Volume: 132 Pages: 1121-5
  • NAID: 120005476152
  • Peer Reviewed
• [Journal Article] Evaluation of nodal response after intra-arterial chemoradiation for node-positive head and neck cancer (2012)
  • Author(s): Sakashita T, Homma A, Oridate N, Hatakeyama H, Kano S, Mizumachi T, Fukuda S
  • Journal Title: Eur Arch Otorhinolaryngol Volume: 269 Pages: 1671-6
  • NAID: 120005946626
  • Peer Reviewed
• [Journal Article] Combined modality therapy for laryngeal cancer with superselective intra-arterial cisplatin infusion and concomitant radiotherapy (2012)
  • Author(s): Taki S, Homma A, Suzuki F, Oridate N, Hatakeyama H, Mizumachi T, Kano S, Furusawa J, Sakashita T, Inamura N, Yoshida D, Onimaru R, Shirato H, Fukuda S
  • Journal Title: Int J Clin Oncol Volume: 17 Pages: 441-6
  • NAID: 10031144330
  • Peer Reviewed
• [Journal Article] 早期舌癌におけるセンチネルリンパ節の領域分布に関する検討 (2012)
  • Author(s): 坂下智博,本間明宏,折舘伸彦,鈴木清護,畠山博充,加納里志,水町貴諭,福田諭
  • Journal Title: 耳展 Volume: 55 Pages: 364-8
  • NAID: 130004911864
• [Journal Article] 切除可能T3、T4上顎洞扁平上皮癌における手術の位置付け. 当院における治療戦略 (2012)
  • Author(s): 本間明宏,折舘伸彦,鈴木清護,鈴木章之,畠山博充,加納里志,水町貴諭,坂下智博,吉田大介,鬼丸力也,土屋和彦,安田耕一,白土博樹,福田諭
  • Journal Title: 耳鼻と臨床 Volume: 58 Pages: 52-56
  • NAID: 130004555582
• [Journal Article] 頭頸部癌化学放射線療法における経管栄養の役割に関する検討 (2012)
  • Author(s): 倉本倫之介,折舘伸彦,本間明宏,及川敬太,藤田香,鈴木清護,畠山博充,加納里志,水町貴諭,坂下智博,福田諭
  • Journal Title: 嚥下医学 Volume: 1 Pages: 359-63
  • Peer Reviewed
• [Journal Article] Improved survival of Japanese patients with human papillomavirus-positive oropharyngeal squamous cell carcinoma (2012)
  • Author(s): Mizumachi T, Kano S, Sakashita T, Hatakeyama H, Suzuki S, Homma A, Oridate N, Fukuda S
  • Journal Title: Int J Clin Oncol Volume: online 31 Issue: 5 Pages: 0-0
  • DOI: 10.1007/s10147-012-0469-6
  • Peer Reviewed
• [Journal Article] Rapid superselective high-dose cisplatin infusion with concomitant radiotherapy for squamous cell carcinoma of the nasal vestibule: a report of two cases. (2012)
  • Author(s): Homma A, Suzuki F, Hatakeyama H, Sakashita T, Yoshida D, et al.
  • Journal Title: Int Canc Conf J Volume: 1 Issue: 4 Pages: 215-219
  • DOI: 10.1007/s13691-012-0044-z
  • NAID: 120005451604
  • Peer Reviewed
• [Journal Article] Combined modality therapy for laryngeal cancer with superselective intra-arterial cisplatin infusion and concomitant radiotherapy. (2012)
  • Author(s): ④ Taki S, Homma A, Suzuki F, Oridate N, Hatakeyama H, Mizumachi T, Kano S, et al.
  • Journal Title: Int J Clin Oncol Volume: 17 Issue: 5 Pages: 441-446
  • DOI: 10.1007/s10147-011-0308-1
  • NAID: 10031144330
  • Peer Reviewed
• [Journal Article] Evaluation of nodal response after intra-arterial chemoradiation for node-positive head and neck cancer (2012)
  • Author(s): Sakashita T, Homma A, Oridate N, Hatakeyama H, Kano S, Mizumachi T, Fukuda S
  • Journal Title: Eur Arch Otorhinolaryngol Volume: 269 Issue: 6 Pages: 1671-1676
  • DOI: 10.1007/s00405-011-1814-5
  • NAID: 120005946626
  • Peer Reviewed
• [Journal Article] Platinum concentration in sentinel lymph nodes after preoperative intra-arterial cisplatin chemotherapy targeting primary tongue cancer (2012)
  • Author(s): Sakashita T, Homma A, Oridate N, Suzuki S, Hatakeyama H, Kano S, Mizumachi T, Yoshida D, Fujima N, Fukuda S
  • Journal Title: Acta Otolaryngol Volume: 132 Issue: 10 Pages: 1121-1125
  • DOI: 10.3109/00016489.2012.680494
  • NAID: 10031131102
  • Peer Reviewed
• [Journal Article] ＜第13回耳鼻咽喉科手術支援システム･ナビ研究会＞早期舌癌におけるセンチネルリンパ節の領域分布に関する検討. (2012)
  • Author(s): 坂下智博, 本間明宏, 折舘伸彦, 鈴木清護, 畠山博充, 加納里志, 水町貴諭他
  • Journal Title: 耳展 Volume: 55 Pages: 364-368
  • Peer Reviewed
• [Journal Article] 頭頸部癌化学放射線療法における経管栄養の役割に関する検討. (2012)
  • Author(s): 倉本倫之介, 折舘伸彦, 本間明宏, 及川敬太, 藤田 香, 鈴木清護, 畠山博充, 加納里志, 水町貴諭他
  • Journal Title: 嚥下医学 Volume: 1 Pages: 359-363
  • Peer Reviewed
• [Journal Article] 【Best articles of the year】舌根癌における放射線同時併用超選択的動注化学療法. (2012)
  • Author(s): 加納里志, 本間明宏, 折舘伸彦, 鈴木章之, 畠山博充, 水町貴諭他
  • Journal Title: 北海道医誌 Volume: 87 Pages: 208-208
• [Journal Article] 【Best articles of the year】口腔癌における超選択的シスプラチン動注化学療法後のセンチネルリンパ節内プラチナ濃度測定. (2012)
  • Author(s): 坂下智博, 本間明宏, 折舘伸彦, 鈴木清護, 畠山博充, 加納里志, 水町貴諭他
  • Journal Title: 北海道医誌 Volume: 87 Pages: 261-261
• [Journal Article] Concomitant weekly cisplatin and radiotherapy for head and neck cancer (2011)
  • Author(s): Homma A, Inamura N, Oridate N, Suzuki S, Hatakeyama H, Mizumachi T, Kano S, Sakashita T, Onimaru R, Yasuda K, Shirato H, Fukuda S
  • Journal Title: Jpn J Clin Oncol Volume: 41 Pages: 980-6
  • Peer Reviewed
• [Journal Article] A case of immunoglobulin 4-related disease with bilateral mass-forming lesions in the nasolacrimal ducts (2011)
  • Author(s): Suzuki M, Mizumachi T, Morita S, Kubota K, Iizuka K
  • Journal Title: J Clin Rheumatol Volume: 17 Pages: 207-10
  • Peer Reviewed
• [Journal Article] Superselective arterial cisplatin infusion with concomitant radiation therapy for base of tongue cancer (2011)
  • Author(s): Kano S, Homma A, Oridate N, Suzuki F, Hatakeyama H, Mizumachi T, Furusawa J, Sakashita T, Yoshida D, Onimaru R, Shirato H, Fukuda S
  • Journal Title: Oral Oncol Volume: 47 Pages: 665-70
  • Peer Reviewed
• [Journal Article] 個別化を目指す薬物療法HPV陽性中咽頭癌に対する個別化治療戦略 (2011)
  • Author(s): 水町貴諭,畠山博充,加納里志,坂下智博,鈴木清護,本間明宏,折舘伸彦,福田諭
  • Journal Title: 頭頸部癌 Volume: 3 Pages: 394-7
  • Peer Reviewed
• [Journal Article] 頭頸部癌患者を支えるチーム医療北海道大学病院の頭頸部がん患者に対する口腔ケアの取り組み (2011)
  • Author(s): 秦浩信,山崎裕,今待賢治,村井知佳,佐藤淳,水町貴諭,加納里志,本間明宏,福田諭,北川善政
  • Journal Title: 頭頸部癌 Volume: 37 Pages: 486-93
  • Peer Reviewed
• [Journal Article] 唾液導管癌におけるHER2の発現解析 (2011)
  • Author(s): 鈴木崇祥,加納里志,折舘伸彦,本間明宏,鈴木清護,畠山博充,水町貴諭,古沢純,坂下智博,福田諭
  • Journal Title: 頭頸部外科 Volume: 21 Pages: 195-201
  • NAID: 10030814649
  • Peer Reviewed
• [Journal Article] 私たちが行っている化学放射線療法後の救済手術における皮膚切開デザインの工夫 (2011)
  • Author(s): 本間明宏,折舘伸彦,鈴木章之,鈴木清護,原敏浩,真栄田裕行,水町貴諭,稲村直哉,福田諭
  • Journal Title: 頭頸部外科 Volume: 21 Pages: 103-6
  • NAID: 10030814451
  • Peer Reviewed
• [Journal Article] 顎下腺悪性腫瘍1次症例の検討 (2011)
  • Author(s): 北尾恭子,本間明宏,折舘伸彦,鈴木清護,鈴木章之,原敏浩,加納里志,水町貴諭,瀧重成,稲村直哉,福田諭
  • Journal Title: 日本耳鼻咽喉科学会会報 Volume: 114 Pages: 126-32
  • NAID: 10029089793
  • Peer Reviewed
• [Journal Article] 鼻副鼻腔腫瘍治療戦略の新しい可能性を探る鼻副鼻腔悪性腫瘍に対する超選択的動注療法 (2011)
  • Author(s): 本間明宏,水町貴諭,原敏浩,福田諭
  • Journal Title: 日本鼻科学会会誌 Pages: 5092-4
  • Peer Reviewed
• [Journal Article] Strategy for personalized treatment of human papillomavirus-positive oropharyngeal squamous cell carcinoma (2011)
  • Author(s): 水町 貴諭
  • Journal Title: Toukeibu Gan Volume: 37 Issue: 3 Pages: 394-397
  • DOI: 10.5981/jjhnc.37.394
  • NAID: 130004510103
  • ISSN: 1349-5747, 1881-8382
  • Peer Reviewed
• [Journal Article] Superselective arterial cisplatin infusion with concomitant radiation therapy for base of tongue cancer (2011)
  • Author(s): Satoshi Kano
  • Journal Title: Oral Oncology Volume: 47 Issue: 7 Pages: 665-670
  • DOI: 10.1016/j.oraloncology.2011.04.015
  • Peer Reviewed
• [Journal Article] Concomitant weekly cisplatin and radiotherapy for head and neck cancer. (2011)
  • Author(s): Homma A, Inamura N, Oridate N, Suzuki S, Hatakeyama H, Mizumachi T,et al.
  • Journal Title: Jpn J Clin Oncol Volume: 41 Issue: 4 Pages: 980-986
  • DOI: 10.1097/rhu.0b013e31821c71a3
  • Peer Reviewed
• [Presentation] Concomitant weekly cisplatin and radiotherapy for HPV-positive oropharyngeal squamous cell carcinoma in Japan (2013)
  • Author(s): Mizumachi T, Homma A, Sakashita T, Kano S, Hatakeyama H, Fukuda S
  • Organizer: AAO-HNS Annual Meeting & OTO EXPO2013
  • Place of Presentation: Vancouver Convention and Exhibition Center (Vancouver, Canada)
• [Presentation] HPV陽性中咽頭癌に対するweekly CDDP併用化学放射線治療の臨床的検討 (2013)
  • Author(s): 水町貴諭、本間明宏、坂下智博、加納里志、畠山博充、福田諭
  • Organizer: 第37回日本頭頸部癌学会
  • Place of Presentation: 京王プラザホテル(東京)
• [Presentation] Combined analysis of HPV status and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma (2013)
  • Author(s): Mizumachi T, Oridate N, Sakashita T, Kano S, Hatakeyama H, Suzuki S, Homma A, Fukuda S
  • Organizer: 20th IFOS World Congress
  • Place of Presentation: COEX convention center (Seoul, Korea)
• [Presentation] Combined analysis of HPV status and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma (2013)
  • Author(s): Mizumachi T, Oridate N, Sakashita T, Kano S, Hatakeyama H, Suzuki S, Homma A, Fukuda S
  • Organizer: 20th IFOS World Congress
  • Place of Presentation: COEX Comvention Center(Seoul, Korea)
• [Presentation] Concomitant weekly cisplatin and radiotherapy for HPV-positive oropharyngeal squamous cell carcinoma in Japan (2013)
  • Author(s): Mizumachi T, Homma A, Sakashita T, Kano S, Hatakeyama H, Fukuda S
  • Organizer: AAO-HNS Annual Meeting & OTO EXPO2013
  • Place of Presentation: Vancouver Convention Centre(Vancouver, Canada)
• [Presentation] HPV陽性中咽頭癌に対するweekly CDDP併用化学放射線治療の臨床的検討 (2013)
  • Author(s): 水町貴諭、本間明宏、坂下智博、加納里志、畠山博充、福田諭
  • Organizer: 第37回日本頭頸部癌学会
  • Place of Presentation: 京王プラザホテル（東京都新宿区）
• [Presentation] 当科における二期的気管食道瘻形成術～弯曲型食道直達鏡の試作 (2012)
  • Author(s): 水町貴諭、本間明宏、坂下智博、加納里志、畠山博充、鈴木清護、折舘伸彦、福田諭
  • Organizer: 第14回耳鼻咽喉科手術支援システム・ナビ研究会
  • Place of Presentation: 東京医科大学(東京)
  • Year and Date: 2012-11-03
• [Presentation] HPV陽性中咽頭癌の転移リンパ節の臨床像 (2012)
  • Author(s): 水町貴諭、加納里志、本間明宏、折舘伸彦、福田諭
  • Organizer: 第25回日本口腔・咽頭科学会
  • Place of Presentation: 熊本県立劇場(熊本市)
• [Presentation] Human papillomavirus in Japanese female laryngeal carcinoma (2012)
  • Author(s): Mizumachi T, Oridate N, Sakashita T, Kano S, Hatakeyama H, Suzuki S, Homma A, Fukuda S
  • Organizer: 8th International Conference on Head & Neck Cancer
  • Place of Presentation: Metro Toronto Convention Centre (Toronto, Canada)
• [Presentation] 中咽頭扁平上皮癌症例におけるHPV感染とp16の発現に関する検討 (2012)
  • Author(s): 水町貴諭、鈴木清護、畠山博充、加納里志、坂下智博、本間明宏、折舘伸彦、福田諭
  • Organizer: 第36回日本頭頸部癌学会
  • Place of Presentation: 島根県民会館(松江市)
• [Presentation] 女性喉頭癌症例におけるHPV感染の検討 (2012)
  • Author(s): 水町貴諭、加納里志、畠山博充、坂下智博、鈴木清護、本間明宏、折舘伸彦、福田諭
  • Organizer: 第113回日本耳鼻咽喉科学会
  • Place of Presentation: 新潟コンベンションセンター(新潟市)
• [Presentation] 喫煙、飲酒歴のない女性の喉頭癌の発症にHPV感染は関与しているか? (2012)
  • Author(s): 水町貴諭、本間明宏、折舘伸彦、福田諭
  • Organizer: 第24回日本喉頭科学会
  • Place of Presentation: 金沢市文化ホール・金沢ニューグランドホテル(金沢市)
• [Presentation] 喉頭癌T3症例の治療成績の検討 (2012)
  • Author(s): 水町貴諭、折舘伸彦、本間明宏、坂下智博、加納里志、畠山博充、鈴木清護、福田諭
  • Organizer: 第22回日本頭頸部外科学会
  • Place of Presentation: 福島ビューホテル・ホテル福島グリーンパレス(福島市)
• [Presentation] 喉頭癌T3 症例の治療成績の検討 (2012)
  • Author(s): 水町 貴諭
  • Organizer: 第22回日本頭頸部外科学会総会ならびに学術講演会
  • Place of Presentation: 福島ビューホテル他（福島県）
• [Presentation] 喫煙、飲酒歴のない女性の喉頭癌の発症にHPV感染は関与しているか？ (2012)
  • Author(s): 第24回日本喉頭科学会総会・学術講演会
  • Organizer: 第24回日本喉頭科学会総会・学術講演会
  • Place of Presentation: 金沢市文化ホール他（金沢県）
• [Presentation] HPV感染による中咽頭癌治療の層別化戦略 (2011)
  • Author(s): 水町貴諭、加納里志、本間明宏、折舘伸彦、福田諭
  • Organizer: 第24回日本口腔・咽頭科学会
  • Place of Presentation: ANAクラウンプラザホテル広島(広島市)
• [Presentation] <パネルディスカッション2>個別化治療を目指す薬物療法、HPV陽性中咽頭癌に対する個別化治療戦略 (2011)
  • Author(s): 水町貴諭、畠山博充、加納里志、坂下智博、鈴木清護、本間明宏、折舘伸彦、福田諭
  • Organizer: 第35回日本頭頸部癌学会
  • Place of Presentation: ウインクあいち(名古屋市)
• [Presentation] HPV陽性中咽頭癌に対する個別化治療戦略 (2011)
  • Author(s): 水町 貴諭
  • Organizer: 第35回日本頭頸部癌学会
  • Place of Presentation: ウインクあいち（愛知県産業労働センター）（愛知県）
• [Presentation] ヒト乳頭腫ウイルス（HPV）と頭頸部癌の臨床 (2011)
  • Author(s): 水町 貴諭
  • Organizer: 第24回日本耳鼻咽喉科学会北海道ブロック講演会(招待講演)
  • Place of Presentation: 北海道大学（札幌市）
• [Presentation] HPV感染による中咽頭癌治療の層別化戦略 (2011)
  • Author(s): 水町 貴諭
  • Organizer: 第24回日本口腔・咽頭科学会総会学術講演会
  • Place of Presentation: ＡＮＡクラウンプラザホテル広島（広島県）
• [Presentation] 女性喉頭癌症例におけるHPV感染の検討.
  • Author(s): 水町貴諭, 加納里志, 畠山博充, 坂下智博, 鈴木清護,他
  • Organizer: 第113回日本耳鼻咽喉科学会
  • Place of Presentation: 朱鷺メッセ(新潟コンベンションセンター)（新潟市）
• [Presentation] 中咽頭扁平上皮癌症例における HPV 感染と p16 の発現に関する検討.
  • Author(s): 水町貴諭, 鈴木清護, 畠山博充, 加納里志, 坂下智博他
  • Organizer: 第36回日本頭頸部癌学会
  • Place of Presentation: 島根県民会館 （松江市）
• [Presentation] Human papillomavirus in Japanese female laryngeal carcinoma.
  • Author(s): Mizumachi T, Oridate N, Sakashita T, Kano S, Hatakeyama H, et al.
  • Organizer: 8th International Conference on Head & Neck Cancer.
  • Place of Presentation: Metro Toronto Convention Centre （カナダ）
• [Presentation] HPV陽性中咽頭癌の転移リンパ節の臨床像.
  • Author(s): 水町貴諭, 加納里志, 本間明宏, 折舘伸彦, 福田 諭
  • Organizer: 第25回日本口腔・咽頭科学会.
  • Place of Presentation: 熊本県立劇場（熊本市）
• [Presentation] 当科における二期的気管食道瘻形成術~弯曲型食道直達鏡の試作.
  • Author(s): 水町貴諭, 本間明宏, 坂下智博, 加納里志, 畠山博充他
  • Organizer: 第14回耳鼻咽喉科手術支援システム・ナビ研究会
  • Place of Presentation: 東京医科大学病院（東京都新宿区）