Pathologic Elucidation of Olfactory Disorder Using Mass Spectrometry
Project/Area Number |
23791897
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Otorhinolaryngology
|
Research Institution | Kobe University |
Principal Investigator |
DOI Kiyoshi 神戸大学, 大学院・医学研究科, 助教 (00379380)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
Keywords | 嗅覚障害 / マイクロアレイ・BDNF / 嗅覚 / 遺伝子 / マイクロアレイ / メタボローム |
Research Abstract |
The olfactory receptor neurons have an unusual characteristic of continuous neurogenesis throughout its lifetime. We observed a dynamic state of gene in the regeneration process of olfactory receptor neurons. From this observation, it was suggested that BDNF, that is known as a neurotrophic factor participates to the olfactory regeneration process at early phase in the olfactory epithelium and at late phase in the olfactory bulb.
|
Report
(3 results)
Research Products
(7 results)